Dutch researcher Niels Cornelisse used computer models to study the electrochemical communication between cells from rat kidneys and cells from the pituitary gland of a toad species. He found many similarities in the coupling of chemical and electrical signals in these completely different cells.
Cells transmit electrical and chemical signals to other cells to coordinate the various cellular activities in the organism. Cornelisse made a mathematical model for the link between the chemical calcium signal and the electrical activity of brain cells. With this model he discovered many similarities between the linking of the electrical and chemical signals in a completely different cell type, the tissue cell, even though the cells studied had completely different functions.
Fundamental knowledge about the manner in which cells communicate with each other, could provide insights into diseases, such as cancer or brain disorders, where something goes wrong with the signal transfer between cells.
Sonja Jacobs | NWO
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