Resource should greatly speed gene analysis and discovery
Researchers have produced vast libraries of short segments of ribonucleic acid (RNA) that can be used to turn off individual human and mouse genes to study their function.
The libraries will be made widely available to laboratories studying human biology and disease. The researchers are optimistic that the libraries will become a powerful research tool for gene analysis and discovery.
Two independent research groups reported on their respective RNA interference (RNAi) libraries in the March 25, 2004, issue of the journal Nature. Gregory Hannon of the Cold Spring Harbor Laboratory and Howard Hughes Medical Institute investigator Stephen J. Elledge at Harvard Medical School and Brigham and Womens Hospital led the first group. The joint lead authors were Patrick Paddison, Jose Silva and Douglas Conklin in Hannons laboratory. René Bernards of The Netherlands Cancer Institute led a second group.
Jim Keeley | EurekAlert!
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