Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:


Breakthrough in plant medicine production

A research team of scientists from Wageningen University and Research Centre in the Netherlands has succeeded in further unravelling and manipulating the glycosylation of proteins in plants.

This is the result of the research soon to be published in the renowned scientific magazine The Plant Cell. The scientists expect that this knowledge will allow plants to be applied more often in the production of therapeutic proteins, an important type of medicine.

The discovery fits in with technology developed by the Wageningen UR research institute Plant Research International for the production of biopharmaceuticals in plants.

Proteins in plants, animals and people are equipped with various sugar chains in a process known as glycosylation. The sugar chains are of significance to the functioning of many proteins. Moreover, their identity and uniformity is crucial to the quality of therapeutic proteins.

... more about:
»Protein »glycosylation

The glycosylation of proteins in plants, people and animals basically consists of three stages. Initially sugar chains are constructed, which then attach to the protein in specific locations. Finally, the sugar chains are further modified as specific sugars are attached to the chain.

“We are the first institute in the world to identify a gene in plants that is involved in the construction of these sugar chains, the first stage in glycosylation,” says scientist Maurice Henquet. “It seems that the chains become increasingly uniform as the expression of this gene is reduced.” One type of chain, a relatively simple one, is mainly developed. The sugar chains which are attached to the proteins are therefore a better starting point for making adjustments that are designed to optimise the biological function as medicine.

“From now on we will be able to improve the manipulation of glycosylation,” Henquet continues. “And plants will become even more suitable for medicine production.”

Jac Niessen | alfa
Further information:

Further reports about: Protein glycosylation

More articles from Life Sciences:

nachricht Biologists unravel another mystery of what makes DNA go 'loopy'
16.03.2018 | Emory Health Sciences

nachricht Scientists map the portal to the cell's nucleus
16.03.2018 | Rockefeller University

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Locomotion control with photopigments

Researchers from Göttingen University discover additional function of opsins

Animal photoreceptors capture light with photopigments. Researchers from the University of Göttingen have now discovered that these photopigments fulfill an...

Im Focus: Surveying the Arctic: Tracking down carbon particles

Researchers embark on aerial campaign over Northeast Greenland

On 15 March, the AWI research aeroplane Polar 5 will depart for Greenland. Concentrating on the furthest northeast region of the island, an international team...

Im Focus: Unique Insights into the Antarctic Ice Shelf System

Data collected on ocean-ice interactions in the little-researched regions of the far south

The world’s second-largest ice shelf was the destination for a Polarstern expedition that ended in Punta Arenas, Chile on 14th March 2018. Oceanographers from...

Im Focus: ILA 2018: Laser alternative to hexavalent chromium coating

At the 2018 ILA Berlin Air Show from April 25–29, the Fraunhofer Institute for Laser Technology ILT is showcasing extreme high-speed Laser Material Deposition (EHLA): A video documents how for metal components that are highly loaded, EHLA has already proved itself as an alternative to hard chrome plating, which is now allowed only under special conditions.

When the EU restricted the use of hexavalent chromium compounds to special applications requiring authorization, the move prompted a rethink in the surface...

Im Focus: Radar for navigation support from autonomous flying drones

At the ILA Berlin, hall 4, booth 202, Fraunhofer FHR will present two radar sensors for navigation support of drones. The sensors are valuable components in the implementation of autonomous flying drones: they function as obstacle detectors to prevent collisions. Radar sensors also operate reliably in restricted visibility, e.g. in foggy or dusty conditions. Due to their ability to measure distances with high precision, the radar sensors can also be used as altimeters when other sources of information such as barometers or GPS are not available or cannot operate optimally.

Drones play an increasingly important role in the area of logistics and services. Well-known logistic companies place great hope in these compact, aerial...

All Focus news of the innovation-report >>>



Industry & Economy
Event News

Ultrafast Wireless and Chip Design at the DATE Conference in Dresden

16.03.2018 | Event News

International Tinnitus Conference of the Tinnitus Research Initiative in Regensburg

13.03.2018 | Event News

International Virtual Reality Conference “IEEE VR 2018” comes to Reutlingen, Germany

08.03.2018 | Event News

Latest News

Wandering greenhouse gas

16.03.2018 | Earth Sciences

'Frequency combs' ID chemicals within the mid-infrared spectral region

16.03.2018 | Physics and Astronomy

Biologists unravel another mystery of what makes DNA go 'loopy'

16.03.2018 | Life Sciences

Science & Research
Overview of more VideoLinks >>>