Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Help for simulation-tools and stroke patients

30.05.2008
Jörg Willems has made an important contribution to our understanding of multi-scale problems in fluid mechanics and thermodynamics. The effects of a stroke can now be significantly alleviated with a stem cell therapy based on umbilical cord blood.

Simulation is an important tool for computer-based development and pretesting of materials, helping eliminate expensive, dangerous mistakes. Computer-based testing is a specialized field of the Fraunhofer Institute for Industrial Mathematics ITWM in Kaiserslautern, not least because materials simulation is a complex process involving a great deal of mathematics.

This is especially true of multiscale materials modeling, the mathematical description of materials across multiple spatial and time scales. Graduate mathematician Jörg Willems has significantly improved our understanding of multiscale problems associated with flow dynamics and thermodynamics. His diploma thesis has greatly facilitated the use of numerical simulation in the development of filter media, insulating materials, composite materials and fuel cells. He has been awarded 2nd place in the Hugo Geiger Prize for his work.

When a stroke is diagnosed, every minute is of high value for limiting its impact. Existing treatment protocols only take effect after three to four hours. Physicians are therefore looking for effective alternatives such as stem cell therapy. Johannes Boltze of the Fraunhofer Institute for Cell Therapy and Immunology IZI in Leipzig is one of them. In his doctoral thesis he established a model for examining strokes in rats, and managed to show that treatment with stem cell containing populations shows promising results: “The ability of untreated animals to move after the infarct is severely impaired,” explains Johannes Boltze. “In behavioural tests, for instance, they have difficulty balancing well enough to run across a bar. Not so in the case of the animals we treated with cells.

... more about:
»Stem »stroke

They nimbly run across again after only a fortnight.” The stem cells promote endogenous healing and organizational processes in the brain. As a result, the surviving nerve cells are probably more resistant to the damage if the treatment is begun within 72 hours after stroke onset. Thus, cells from umbilical cord blood and bone marrow could be used for the stroke trials – an uncontroversial method that avoids any ethical concerns. The cell therapy procedure is ideal for further clinical usage in a stroke unit. Dr. Johannes Boltze received the 3rd place in the Hugo Geiger Prize for his research work.

Press Office | alfa
Further information:
http://www.fraunhofer.de/EN/press/pi/2008/05/ResearchNews5s2008Topic6.jsp

Further reports about: Stem stroke

More articles from Life Sciences:

nachricht Warming ponds could accelerate climate change
21.02.2017 | University of Exeter

nachricht An alternative to opioids? Compound from marine snail is potent pain reliever
21.02.2017 | University of Utah

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Breakthrough with a chain of gold atoms

In the field of nanoscience, an international team of physicists with participants from Konstanz has achieved a breakthrough in understanding heat transport

In the field of nanoscience, an international team of physicists with participants from Konstanz has achieved a breakthrough in understanding heat transport

Im Focus: DNA repair: a new letter in the cell alphabet

Results reveal how discoveries may be hidden in scientific “blind spots”

Cells need to repair damaged DNA in our genes to prevent the development of cancer and other diseases. Our cells therefore activate and send “repair-proteins”...

Im Focus: Dresdner scientists print tomorrow’s world

The Fraunhofer IWS Dresden and Technische Universität Dresden inaugurated their jointly operated Center for Additive Manufacturing Dresden (AMCD) with a festive ceremony on February 7, 2017. Scientists from various disciplines perform research on materials, additive manufacturing processes and innovative technologies, which build up components in a layer by layer process. This technology opens up new horizons for component design and combinations of functions. For example during fabrication, electrical conductors and sensors are already able to be additively manufactured into components. They provide information about stress conditions of a product during operation.

The 3D-printing technology, or additive manufacturing as it is often called, has long made the step out of scientific research laboratories into industrial...

Im Focus: Mimicking nature's cellular architectures via 3-D printing

Research offers new level of control over the structure of 3-D printed materials

Nature does amazing things with limited design materials. Grass, for example, can support its own weight, resist strong wind loads, and recover after being...

Im Focus: Three Magnetic States for Each Hole

Nanometer-scale magnetic perforated grids could create new possibilities for computing. Together with international colleagues, scientists from the Helmholtz Zentrum Dresden-Rossendorf (HZDR) have shown how a cobalt grid can be reliably programmed at room temperature. In addition they discovered that for every hole ("antidot") three magnetic states can be configured. The results have been published in the journal "Scientific Reports".

Physicist Dr. Rantej Bali from the HZDR, together with scientists from Singapore and Australia, designed a special grid structure in a thin layer of cobalt in...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Booth and panel discussion – The Lindau Nobel Laureate Meetings at the AAAS 2017 Annual Meeting

13.02.2017 | Event News

Complex Loading versus Hidden Reserves

10.02.2017 | Event News

International Conference on Crystal Growth in Freiburg

09.02.2017 | Event News

 
Latest News

Impacts of mass coral die-off on Indian Ocean reefs revealed

21.02.2017 | Earth Sciences

Novel breast tomosynthesis technique reduces screening recall rate

21.02.2017 | Medical Engineering

Use your Voice – and Smart Homes will “LISTEN”

21.02.2017 | Trade Fair News

VideoLinks
B2B-VideoLinks
More VideoLinks >>>