Dr. Daniel Dries, left, and Dr. Mark Drazner found that enalapril, an ACE inhibitor commonly given to patients with heart failure, is just as effective for black patients with heart failure as it is for white patients.
A drug widely used to treat patients with heart failure is as effective for black patients as it is for white patients, according to researchers at UT Southwestern Medical Center at Dallas.
The results of this analysis do not support the hypothesis that black patients with heart failure may not respond as well to angiotensin-converting enzyme (ACE) inhibitors as white patients with heart failure, said Dr. Daniel Dries, lead author of the study in today’s issue of the Journal of the American College of Cardiology and assistant professor of internal medicine at UT Southwestern.
"Although the black participants responded equally well to the ACE-inhibitor as white participants, they still had overall increased rates of progression to heart failure," Dries said. "The precise explanation for the racial differences in the natural history of asymptomatic reductions in pump function is not known, but these data indicate that it is not explained by racial differences in response to ACE-inhibitor therapy."
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