During the past twelve months Genedata Screener has provided computational support throughout a complete screening cycle at Chugai. Beginning with assay optimization and followed by primary and validation screening phases, Screener has enhanced Chugai’s search for active compounds with more robust measures for biological effects within the screening cascade.
Genedata’s computational scientists in Japan, based in Tokyo, have integrated Genedata Screener with research infrastructure at Chugai. It has been connected to Chugai’s screening platforms and result databases, providing data quality assurance and automating the analysis process from the plate readers all the way to the corporate databases.
Chugai’s screening experts use the AssayAnalyzer module to gain an overview of data quality for entire screening campaigns. Genedata’s Condoseo module is used to estimate the potency of compounds screened at multiple concentrations in the validation screening phase.
Actions speak louder than words
Genedata’s collaboration with Chugai began with a case study performed on data generated at Chugai’s research facilities in Kamkura, near Tokyo. Genedata analyzed a complete data set composed of primary and validation screening data, and presented the results to Chugai’s scientists.
The case study demonstrated the speed and efficiency of Genedata’s computational approach to screening analysis. “Data visualization and data quality assurance were key drivers behind choosing Genedata’s solution”, explained Hiroki Takaya, Group Manager, Pharmaceutical Technology Department, Chugai Pharmaceutical Co., Ltd.
This is Genedata Screener’s first collaboration in Japan. “We are strengthening our customer base internationally and our success with Chugai validates our approach to achieving close collaboration with customers on a global scale”, said Dr. Stephan Heyse, Head of Genedata Screener, Genedata AG.
tobe freeman | alfa
Construction of practical quantum computers radically simplified
05.12.2016 | University of Sussex
UT professor develops algorithm to improve online mapping of disaster areas
29.11.2016 | University of Tennessee at Knoxville
Have you ever wondered how you see the world? Vision is about photons of light, which are packets of energy, interacting with the atoms or molecules in what...
A multi-institutional research collaboration has created a novel approach for fabricating three-dimensional micro-optics through the shape-defined formation of porous silicon (PSi), with broad impacts in integrated optoelectronics, imaging, and photovoltaics.
Working with colleagues at Stanford and The Dow Chemical Company, researchers at the University of Illinois at Urbana-Champaign fabricated 3-D birefringent...
In experiments with magnetic atoms conducted at extremely low temperatures, scientists have demonstrated a unique phase of matter: The atoms form a new type of quantum liquid or quantum droplet state. These so called quantum droplets may preserve their form in absence of external confinement because of quantum effects. The joint team of experimental physicists from Innsbruck and theoretical physicists from Hannover report on their findings in the journal Physical Review X.
“Our Quantum droplets are in the gas phase but they still drop like a rock,” explains experimental physicist Francesca Ferlaino when talking about the...
The Max Planck Institute for Physics (MPP) is opening up a new research field. A workshop from November 21 - 22, 2016 will mark the start of activities for an innovative axion experiment. Axions are still only purely hypothetical particles. Their detection could solve two fundamental problems in particle physics: What dark matter consists of and why it has not yet been possible to directly observe a CP violation for the strong interaction.
The “MADMAX” project is the MPP’s commitment to axion research. Axions are so far only a theoretical prediction and are difficult to detect: on the one hand,...
Broadband rotational spectroscopy unravels structural reshaping of isolated molecules in the gas phase to accommodate water
In two recent publications in the Journal of Chemical Physics and in the Journal of Physical Chemistry Letters, researchers around Melanie Schnell from the Max...
16.11.2016 | Event News
01.11.2016 | Event News
14.10.2016 | Event News
06.12.2016 | Health and Medicine
06.12.2016 | Life Sciences
05.12.2016 | Power and Electrical Engineering