By outrunning a laser’s path of destruction, an international research team has created 3D images of fragile but biologically important molecules inside protein nanocrystals. Using the Linac Coherence Light Source (LCLS), a powerful X-ray laser at the SLAC National Accelerator Laboratory in Menlo Park, Calif., the scientists fired femtosecond (one quadrillionth of a second) bursts of light at a stream of tumbling molecules, obliterating them as they pass, but not before capturing otherwise illusive images of their crystalline structures.
An overview and early results of this new imaging technique will be presented at the 2012 meeting of the American Crystallographic Association (ACA), which takes place July 28 – Aug. 1 in Boston, Mass.“These laser pulses are so brief that we are able to outrun the radiation’s damaging effects,” said John C.H. Spence of Arizona State University, one of more than 70 international researchers from institutions including SLAC; DESY, the German Electron Synchrotron; and the Max-Planck Institute in Heidelberg, Germany.
To obtain images of these molecules in the more natural state, the researchers sent the protein nanocrystals streaming in a single-file micron-sized droplet beam (rather like an ink-jet printer) in vacuum across the X-ray beam, in a method developed at Arizona State University.Next they fired incredibly brief bursts of X-ray laser light, about 100 times each second, at the molecules in the droplet beam, and detected the scattered X-ray patterns from each particle before the intensity of the beam blasted them apart. The researchers were able to combine these millions of snapshots to build up 3D models of the molecules with atomic-scale resolution.
A complete listing of the collaborating research institutions follows:
Catherine Meyers | Newswise Science News
Further reports about: > ACA > Advanced Investigator Grant > Ancient Mass Extinction > Arizona > Biochemistry > Biophysics > CHEMISTRY > Crystallographic > DESY > LCLS > Max-Planck-Institut > Molecular Target > Physic > Power Plant Technology > X-ray > X-ray microscopy > X-rays > chemical bond > chemical reaction > international research > laser light > laser system > radiation damage > room temperature
ALMA discovers aluminum around young star
17.05.2019 | National Institutes of Natural Sciences
JQI researchers shed new light on atomic 'wave function'
17.05.2019 | National Institute of Standards and Technology (NIST)
Engineers at the University of Tokyo continually pioneer new ways to improve battery technology. Professor Atsuo Yamada and his team recently developed a...
With a quantum coprocessor in the cloud, physicists from Innsbruck, Austria, open the door to the simulation of previously unsolvable problems in chemistry, materials research or high-energy physics. The research groups led by Rainer Blatt and Peter Zoller report in the journal Nature how they simulated particle physics phenomena on 20 quantum bits and how the quantum simulator self-verified the result for the first time.
Many scientists are currently working on investigating how quantum advantage can be exploited on hardware already available today. Three years ago, physicists...
'Quantum technologies' utilise the unique phenomena of quantum superposition and entanglement to encode and process information, with potentially profound benefits to a wide range of information technologies from communications to sensing and computing.
However a major challenge in developing these technologies is that the quantum phenomena are very fragile, and only a handful of physical systems have been...
Working group led by physicist Professor Ulrich Nowak at the University of Konstanz, in collaboration with a team of physicists from Johannes Gutenberg University Mainz, demonstrates how skyrmions can be used for the computer concepts of the future
When it comes to performing a calculation destined to arrive at an exact result, humans are hopelessly inferior to the computer. In other areas, humans are...
Scientists develop a molecular recording tool that enables in vivo lineage tracing of embryonic cells
The beginning of new life starts with a fascinating process: A single cell gives rise to progenitor cells that eventually differentiate into the three germ...
29.04.2019 | Event News
17.04.2019 | Event News
15.04.2019 | Event News
17.05.2019 | Materials Sciences
17.05.2019 | Physics and Astronomy
17.05.2019 | Materials Sciences