Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Wheezing After Early-Life Antibiotics: Blame the Underlying Chest Infection More Than the Antibiotics

07.08.2008
Children who are given antibiotics in their first three months often wheeze at 15 months of age. However, this wheezing is probably more due to the presence of chest infections than to the use of antibiotics.

These were the key findings of research carried out by researchers in New Zealand, and published in this month’s edition of Clinical and Experimental Allergy.

This work built on the fact that the prevalence both of asthma and the use of antibiotics have risen since the 1960s. Using antibiotics reduces a person’s exposure to bacterial infections and disturbs healthy populations of bacteria in the body, and the question is whether this then leaves a person more prone to develop asthma.

The researchers recruited a group of 1,000 babies at birth and contacted the parents at 3 months, 15 months and then yearly until they were four years old. Each time, they collected data about chest infections, asthma and their use of antibiotics. The data showed that by the time the children had reached 15 months old, nearly three quarters (72.1%) had been given antibiotics. In addition 11.8% had asthma, 39.6% had eczema and 21.2% had a recurring itchy scaly rash.

The researchers then looked at the data to see whether there was any indication that the antibiotics caused these effects and found that by adjusting for the effects of chest infections the association between antibiotics and wheezing was very much reduced.

"Our results strongly suggest that the reason that some children who have been given antibiotics appear to develop asthma is because they had a chest infection and the symptoms of the chest infection in young children can be confused with the start of asthma,” says Julian Crane, a senior study investigator at the Wellington Asthma Research Group in Wellington, New Zealand. “Antibiotics are given to treat the respiratory condition and rather than being a cause of asthma, as has been previously suggested, they are used for chest infections which can indicate an increased risk of asthma, or be mistaken for it.”

One of the underlying issues is that it is often difficult to distinguish between asthma and chest infections at an early age. Consequently some infants who are given antibiotics to cure a chest infection may really have been suffering from the early symptoms of asthma.

“Our data still leaves open the possibility that antibiotics may affect the development of eczema and itchy skin by four years and allergic hypersensitivity by 15 months,” says Crane.

Jennifer Beal | alfa
Further information:
http://www.wiley.co.uk

More articles from Health and Medicine:

nachricht Unique brain 'fingerprint' can predict drug effectiveness
11.07.2018 | McGill University

nachricht Direct conversion of non-neuronal cells into nerve cells
03.07.2018 | Universitätsmedizin der Johannes Gutenberg-Universität Mainz

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: First evidence on the source of extragalactic particles

For the first time ever, scientists have determined the cosmic origin of highest-energy neutrinos. A research group led by IceCube scientist Elisa Resconi, spokesperson of the Collaborative Research Center SFB1258 at the Technical University of Munich (TUM), provides an important piece of evidence that the particles detected by the IceCube neutrino telescope at the South Pole originate from a galaxy four billion light-years away from Earth.

To rule out other origins with certainty, the team led by neutrino physicist Elisa Resconi from the Technical University of Munich and multi-wavelength...

Im Focus: Magnetic vortices: Two independent magnetic skyrmion phases discovered in a single material

For the first time a team of researchers have discovered two different phases of magnetic skyrmions in a single material. Physicists of the Technical Universities of Munich and Dresden and the University of Cologne can now better study and understand the properties of these magnetic structures, which are important for both basic research and applications.

Whirlpools are an everyday experience in a bath tub: When the water is drained a circular vortex is formed. Typically, such whirls are rather stable. Similar...

Im Focus: Breaking the bond: To take part or not?

Physicists working with Roland Wester at the University of Innsbruck have investigated if and how chemical reactions can be influenced by targeted vibrational excitation of the reactants. They were able to demonstrate that excitation with a laser beam does not affect the efficiency of a chemical exchange reaction and that the excited molecular group acts only as a spectator in the reaction.

A frequently used reaction in organic chemistry is nucleophilic substitution. It plays, for example, an important role in in the synthesis of new chemical...

Im Focus: New 2D Spectroscopy Methods

Optical spectroscopy allows investigating the energy structure and dynamic properties of complex quantum systems. Researchers from the University of Würzburg present two new approaches of coherent two-dimensional spectroscopy.

"Put an excitation into the system and observe how it evolves." According to physicist Professor Tobias Brixner, this is the credo of optical spectroscopy....

Im Focus: Chemical reactions in the light of ultrashort X-ray pulses from free-electron lasers

Ultra-short, high-intensity X-ray flashes open the door to the foundations of chemical reactions. Free-electron lasers generate these kinds of pulses, but there is a catch: the pulses vary in duration and energy. An international research team has now presented a solution: Using a ring of 16 detectors and a circularly polarized laser beam, they can determine both factors with attosecond accuracy.

Free-electron lasers (FELs) generate extremely short and intense X-ray flashes. Researchers can use these flashes to resolve structures with diameters on the...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

Leading experts in Diabetes, Metabolism and Biomedical Engineering discuss Precision Medicine

13.07.2018 | Event News

Conference on Laser Polishing – LaP: Fine Tuning for Surfaces

12.07.2018 | Event News

11th European Wood-based Panel Symposium 2018: Meeting point for the wood-based materials industry

03.07.2018 | Event News

 
Latest News

Subaru Telescope helps pinpoint origin of ultra-high energy neutrino

16.07.2018 | Physics and Astronomy

Barium ruthenate: A high-yield, easy-to-handle perovskite catalyst for the oxidation of sulfides

16.07.2018 | Life Sciences

New research calculates capacity of North American forests to sequester carbon

16.07.2018 | Earth Sciences

VideoLinks
Science & Research
Overview of more VideoLinks >>>