Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Cooling lessens brain damage in sick newborn babies

28.01.2005


Cooling the brains of babies deprived of oxygen at birth can reduce the risk of brain damage and cerebral palsy, according to an international study published today (January 28) in the Lancet on-line.



To achieve cooling, the body temperature of babies in the trial was lowered by 3-4 degrees for 72 hours after birth using a water-filled cap.

The research was undertaken in hospitals in North America, New Zealand and the UK, and the UK arm of the trial was carried out in University College London Hospital, the University of Bristol at St Michael’s and Southmead Hospitals, and Imperial College London at Hammersmith Hospital.


Babies were recruited if there was evidence that the infant had received an inadequate supply of oxygen to the brain during delivery, and when electrical activity from the brain indicated a high risk of brain injury.

The trial, which was supported by Olympic Medical from Seattle, USA indicates that, for some babies, cooling can significantly reduce brain damage. "This demonstrates for the first time that treatment may be possible for babies who suffer oxygen deprivation at birth", comments Professor Marianne Thoresen from Bristol University. Most of the English babies were treated in the Bristol hospitals.

It was discovered some years ago that when the brain is starved of oxygen at birth damage does not occur immediately; instead, as Professor John Wyatt of University College London points out, "a chemical cascade is triggered leading to brain damage hours or days afterwards".

The cooling study results from a long series of studies begun a decade ago when the UK researchers started to work on the problem together with a group from the University of Auckland in New Zealand. In experiments they found that cooling prevented the chemical cascade from causing permanent brain damage, and developed the discovery to the point where the treatment could be tested in babies.

"The success of this long scientific collaboration is a great example of UK institutions working together to be international leaders, able to collaborate effectively and fruitfully with researchers around the world" comments Professor David Edwards from Imperial College.

However, Bristol researcher Professor Andrew Whitelaw points out that: ’We need to get further information on the timing and methods of cooling, as well as which babies are most suitable for treatment, before cooling becomes the standard of care for oxygen deprived babies".

Cherry Lewis | EurekAlert!
Further information:
http://www.bristol.ac.uk

More articles from Health and Medicine:

nachricht Using fragment-based approaches to discover new antibiotics
21.06.2018 | SLAS (Society for Laboratory Automation and Screening)

nachricht Scientists learn more about how gene linked to autism affects brain
19.06.2018 | Cincinnati Children's Hospital Medical Center

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Temperature-controlled fiber-optic light source with liquid core

In a recent publication in the renowned journal Optica, scientists of Leibniz-Institute of Photonic Technology (Leibniz IPHT) in Jena showed that they can accurately control the optical properties of liquid-core fiber lasers and therefore their spectral band width by temperature and pressure tuning.

Already last year, the researchers provided experimental proof of a new dynamic of hybrid solitons– temporally and spectrally stationary light waves resulting...

Im Focus: Overdosing on Calcium

Nano crystals impact stem cell fate during bone formation

Scientists from the University of Freiburg and the University of Basel identified a master regulator for bone regeneration. Prasad Shastri, Professor of...

Im Focus: AchemAsia 2019 will take place in Shanghai

Moving into its fourth decade, AchemAsia is setting out for new horizons: The International Expo and Innovation Forum for Sustainable Chemical Production will take place from 21-23 May 2019 in Shanghai, China. With an updated event profile, the eleventh edition focusses on topics that are especially relevant for the Chinese process industry, putting a strong emphasis on sustainability and innovation.

Founded in 1989 as a spin-off of ACHEMA to cater to the needs of China’s then developing industry, AchemAsia has since grown into a platform where the latest...

Im Focus: First real-time test of Li-Fi utilization for the industrial Internet of Things

The BMBF-funded OWICELLS project was successfully completed with a final presentation at the BMW plant in Munich. The presentation demonstrated a Li-Fi communication with a mobile robot, while the robot carried out usual production processes (welding, moving and testing parts) in a 5x5m² production cell. The robust, optical wireless transmission is based on spatial diversity; in other words, data is sent and received simultaneously by several LEDs and several photodiodes. The system can transmit data at more than 100 Mbit/s and five milliseconds latency.

Modern production technologies in the automobile industry must become more flexible in order to fulfil individual customer requirements.

Im Focus: Sharp images with flexible fibers

An international team of scientists has discovered a new way to transfer image information through multimodal fibers with almost no distortion - even if the fiber is bent. The results of the study, to which scientist from the Leibniz-Institute of Photonic Technology Jena (Leibniz IPHT) contributed, were published on 6thJune in the highly-cited journal Physical Review Letters.

Endoscopes allow doctors to see into a patient’s body like through a keyhole. Typically, the images are transmitted via a bundle of several hundreds of optical...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

Munich conference on asteroid detection, tracking and defense

13.06.2018 | Event News

2nd International Baltic Earth Conference in Denmark: “The Baltic Sea region in Transition”

08.06.2018 | Event News

ISEKI_Food 2018: Conference with Holistic View of Food Production

05.06.2018 | Event News

 
Latest News

Graphene assembled film shows higher thermal conductivity than graphite film

22.06.2018 | Materials Sciences

Fast rising bedrock below West Antarctica reveals an extremely fluid Earth mantle

22.06.2018 | Earth Sciences

Zebrafish's near 360 degree UV-vision knocks stripes off Google Street View

22.06.2018 | Life Sciences

VideoLinks
Science & Research
Overview of more VideoLinks >>>