Cross-section of an aneurysm superimposted over aorta and branching vessels from an atherosclerotic mouse. Lipids in aneurysm and atherosclerotic lesions appear in red. Credit: Lei Zhao, Tim Cyrus, Rolf Grabner/Nature Medicine 10(9): 966-73
Possible implications for some anti-inflammatory drugs used in fighting cardiovascular disease
Very little is known about how aortic aneurysms initially form and progress. Now, researchers from the University of Pennsylvania School of Medicine have shown in an atherosclerotic animal model that susceptibility for developing aneurysms increases significantly when an inflammation pathway important in asthma is activated. Mice without the inflammation gene were protected from aneurysms.
Colin D. Funk, PhD, former Professor of Pharmacology and Medicine, and Lei Zhao, MD, PhD, Research Associate, both in Penn’s Center for Experimental Therapeutics, report their findings in this week’s online publication and the September issue of Nature Medicine. Funk is now the Canada Research Chair in Molecular, Cellular and Physiological Medicine, Queen’s University, Kingston, Canada.
Karen Kreeger | EurekAlert!
Purdue cancer identity technology makes it easier to find a tumor's 'address'
16.11.2018 | Purdue University
Microgel powder fights infection and helps wounds heal
14.11.2018 | Michigan Technological University
Researchers at the University of New Hampshire have captured a difficult-to-view singular event involving "magnetic reconnection"--the process by which sparse particles and energy around Earth collide producing a quick but mighty explosion--in the Earth's magnetotail, the magnetic environment that trails behind the planet.
Magnetic reconnection has remained a bit of a mystery to scientists. They know it exists and have documented the effects that the energy explosions can...
Biochips have been developed at TU Wien (Vienna), on which tissue can be produced and examined. This allows supplying the tissue with different substances in a very controlled way.
Cultivating human cells in the Petri dish is not a big challenge today. Producing artificial tissue, however, permeated by fine blood vessels, is a much more...
Faster and secure data communication: This is the goal of a new joint project involving physicists from the University of Würzburg. The German Federal Ministry of Education and Research funds the project with 14.8 million euro.
In our digital world data security and secure communication are becoming more and more important. Quantum communication is a promising approach to achieve...
On Saturday, 10 November 2018, the research icebreaker Polarstern will leave its homeport of Bremerhaven, bound for Cape Town, South Africa.
When choosing materials to make something, trade-offs need to be made between a host of properties, such as thickness, stiffness and weight. Depending on the application in question, finding just the right balance is the difference between success and failure
Now, a team of Penn Engineers has demonstrated a new material they call "nanocardboard," an ultrathin equivalent of corrugated paper cardboard. A square...
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16.11.2018 | Life Sciences