With new technology that uses short strands of genetic material to shut down a specific gene, researchers have regulated immune system proteins to boost production of cells that seek and destroy cancer cells. This approach may improve the effectiveness of vaccines in the treatment of tumors, including malignant brain tumors.
Results of the study appear in the June issue of the European Journal of Immunology, and the research was conducted at Cedars-Sinais Maxine Dunitz Neurosurgical Institute, where clinical trials of dendritic cell immunotherapy have been underway for several years.
Dendritic cells are the immune systems most potent antigen-presenting cells – those that identify "foreign" substances for destruction. Because cancer cells often are not recognized by dendritic cells as antigens, the neurosurgeons and other scientists at the Institute have developed and studied a vaccine in the treatment of highly aggressive brain tumors called gliomas. They combine in the laboratory tumor cells that have been surgically removed and dendritic cells derived from a patients blood. The new cells are injected back into the patient to seek out other cancer cells for destruction.
Sandra Van | Van Communications
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Scientists at the Max Planck Institute for Polymer Research (MPI-P) in Mainz (Germany) together with scientists from Dresden, Leipzig, Sofia (Bulgaria) and Madrid (Spain) have now developed and characterized a novel, metal-organic material which displays electrical properties mimicking those of highly crystalline silicon. The material which can easily be fabricated at room temperature could serve as a replacement for expensive conventional inorganic materials used in optoelectronics.
Silicon, a so called semiconductor, is currently widely employed for the development of components such as solar cells, LEDs or computer chips. High purity...
Augsburg chemists present a new technology for compressing, storing and transporting highly volatile gases in porous frameworks/New prospects for gas-powered vehicles
Storage of highly volatile gases has always been a major technological challenge, not least for use in the automotive sector, for, for example, methane or...
When we put water in a freezer, water molecules crystallize and form ice. This change from one phase of matter to another is called a phase transition. While this transition, and countless others that occur in nature, typically takes place at the same fixed conditions, such as the freezing point, one can ask how it can be influenced in a controlled way.
We are all familiar with such control of the freezing transition, as it is an essential ingredient in the art of making a sorbet or a slushy. To make a cold...
Thin organic layers provide machines and equipment with new functions. They enable, for example, tiny energy recuperators. In future, these will be installed...
Das Zusammenspiel aus Struktur und Dynamik bestimmt die Funktion von Proteinen, den molekularen Werkzeugen der Zelle. Durch Fortschritte in der...
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17.10.2018 | Life Sciences