From within the rich fabric of connecting tissue between cells, researchers of four institutions, led by the University of Illinois at Urbana-Champaign, have identified the action of anastellin, a natural agent that is showing promise blocking metastasis of cancer cells and enhancing wound healing.
FN-III-1 during unraveling (bottom). Red (top and below) depicts the strong sheet (anastellin). Green depicts the weak sheet.
That anastellin is derived from the cell adhesion protein fibronectin found in the extracellular matrix surrounding cells was known. Researchers at the Burnham Institute in California in September had documented the molecular structure of anastellin, but its ability to initiate matrix assembly and block the spread of cancer cells remained a mystery.
Using crystallography, atomic force microscopy and advanced computer modeling, researchers sorted the chemical structure and mechanical strength of the known fibronectin proteins that glue together myriads of cells in mammalian body tissues.
Jim Barlow | EurekAlert!
Purdue cancer identity technology makes it easier to find a tumor's 'address'
16.11.2018 | Purdue University
Microgel powder fights infection and helps wounds heal
14.11.2018 | Michigan Technological University
Researchers at the University of New Hampshire have captured a difficult-to-view singular event involving "magnetic reconnection"--the process by which sparse particles and energy around Earth collide producing a quick but mighty explosion--in the Earth's magnetotail, the magnetic environment that trails behind the planet.
Magnetic reconnection has remained a bit of a mystery to scientists. They know it exists and have documented the effects that the energy explosions can...
Biochips have been developed at TU Wien (Vienna), on which tissue can be produced and examined. This allows supplying the tissue with different substances in a very controlled way.
Cultivating human cells in the Petri dish is not a big challenge today. Producing artificial tissue, however, permeated by fine blood vessels, is a much more...
Faster and secure data communication: This is the goal of a new joint project involving physicists from the University of Würzburg. The German Federal Ministry of Education and Research funds the project with 14.8 million euro.
In our digital world data security and secure communication are becoming more and more important. Quantum communication is a promising approach to achieve...
On Saturday, 10 November 2018, the research icebreaker Polarstern will leave its homeport of Bremerhaven, bound for Cape Town, South Africa.
When choosing materials to make something, trade-offs need to be made between a host of properties, such as thickness, stiffness and weight. Depending on the application in question, finding just the right balance is the difference between success and failure
Now, a team of Penn Engineers has demonstrated a new material they call "nanocardboard," an ultrathin equivalent of corrugated paper cardboard. A square...
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06.11.2018 | Event News
19.11.2018 | Materials Sciences
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19.11.2018 | Life Sciences