Study in Transplantation provides strong support for the development of therapeutics utilizing companys proprietary peptide technology
Zengen, Inc. announced today that its scientists have discovered a novel approach to reduce organ rejection based on the Companys proprietary research with alpha-Melanocyte-Stimulating Hormone (a-MSH). The research shows that treatment with the a-MSH peptide caused a significant increase in allograft (transplanted tissue) survival and a marked decrease in leukocyte (or white blood cell) infiltration, one of the main causes of infection leading to organ rejection. The study entitled, "a-Melanocyte-Stimulating Hormone Protects the Allograft in Experimental Heart Transplantation," appears in the December 15th issue of Transplantation.
"These results demonstrate that the protection of the transplanted tissue from early injury with a-MSH treatment can postpone rejection," said James Lipton, Ph.D., chief scientific officer and director of Zengen. "This is an important and encouraging advance in the field of organ transplantation and these data provide strong support for the development of anti-rejection therapies utilizing our proprietary peptide molecules based on the larger a-MSH peptide."
Kathy Vincent | EurekAlert!
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