Like other adolescents, some of the 330 young people in the study (from 15 sites across the U.S.) have initiated sexual activity, with many reporting having unprotected sex.
Of the youth who were asked about disclosure of their HIV status to their first sexual partners, the majority reported that they had not disclosed to their partner prior to sexual activity, researchers found. While sexual activity is not uncommon among adolescents, HIV-infected or not, "HIV infection adds another level of complexity to the adolescence of youth who are infected and has implications for both their own health and that of their sexual partners," said lead study author Katherine Tassiopoulos, DSc, MPH, of the Harvard School of Public Health.
The link between not following regimens for antiretroviral therapy (ART) medications — known as non-adherence—and risky sexual behaviors, already recognized among HIV-positive adults, is just now coming to light in adolescents as this cohort emerges from childhood. "Among youth, both non-adherence and sexual initiation may be expressions of independence or of the desire to feel accepted by peers," the authors noted. Successful interventions may account for adolescents' growing desire for independence by encouraging medication adherence, disclosure, and condom use as behaviors that will protect the health of their sexual partners as well as their own.
Early action by clinicians can help prepare these youth to make choices that reduce risk to themselves and to their partners. A critical step is informing youth of their HIV status. In this study, 18 percent of the participants were unaware they were HIV-positive at the time they started sexual activity. Clinicians and families should ensure that young people with HIV are informed of their HIV status prior to or during early adolescence, according to current guidelines for disclosure of HIV infection to children and adolescents.
Researchers found that among sexually active youth with high viral load (> 5,000 copies/ml), 81 percent had drug-resistant virus. This raises the possibility of resistant virus being transmitted to sexual partners and also limits treatment options for infected youth. Author George R. Seage III, DSc, MPH, also of the Harvard School of Public Health, believes that one critical step in encouraging optimal adherence may be informing young people "that ART can dramatically reduce the likelihood of sexual transmission of HIV."
Although the three-pronged message—safer sex practices, disclosure of HIV status to sexual partners, and adherence to ART regimens—is not new, targeted and innovative intervention strategies are needed to reach this important group of adolescents and reinforce healthy behaviors, the team of authors concluded.
The study is available online. It is embargoed until 12:01 a.m. EDT on Thursday, Nov. 8, 2012:
Sexual Risk Behavior Among Youth With Perinatal HIV Infection in the United States: Predictors and Implications for Intervention Development
Clinical Infectious Diseases is a leading journal in the field of infectious disease with a broad international readership. The journal publishes articles on a variety of subjects of interest to practitioners and researchers. Topics range from clinical descriptions of infections, public health, microbiology, and immunology to the prevention of infection, the evaluation of current and novel treatments, and the promotion of optimal practices for diagnosis and treatment. The journal publishes original research, editorial commentaries, review articles, and practice guidelines and is among the most highly cited journals in the field of infectious diseases. Clinical Infectious Diseases is an official publication of the Infectious Diseases Society of America (IDSA). Based in Arlington, Va., IDSA is a professional society representing nearly 10,000 physicians and scientists who specialize in infectious diseases. For more information, visit www.idsociety.org.
Jerica Pitts | EurekAlert!
Using fragment-based approaches to discover new antibiotics
21.06.2018 | SLAS (Society for Laboratory Automation and Screening)
Scientists learn more about how gene linked to autism affects brain
19.06.2018 | Cincinnati Children's Hospital Medical Center
In a recent publication in the renowned journal Optica, scientists of Leibniz-Institute of Photonic Technology (Leibniz IPHT) in Jena showed that they can accurately control the optical properties of liquid-core fiber lasers and therefore their spectral band width by temperature and pressure tuning.
Already last year, the researchers provided experimental proof of a new dynamic of hybrid solitons– temporally and spectrally stationary light waves resulting...
Scientists from the University of Freiburg and the University of Basel identified a master regulator for bone regeneration. Prasad Shastri, Professor of...
Moving into its fourth decade, AchemAsia is setting out for new horizons: The International Expo and Innovation Forum for Sustainable Chemical Production will take place from 21-23 May 2019 in Shanghai, China. With an updated event profile, the eleventh edition focusses on topics that are especially relevant for the Chinese process industry, putting a strong emphasis on sustainability and innovation.
Founded in 1989 as a spin-off of ACHEMA to cater to the needs of China’s then developing industry, AchemAsia has since grown into a platform where the latest...
The BMBF-funded OWICELLS project was successfully completed with a final presentation at the BMW plant in Munich. The presentation demonstrated a Li-Fi communication with a mobile robot, while the robot carried out usual production processes (welding, moving and testing parts) in a 5x5m² production cell. The robust, optical wireless transmission is based on spatial diversity; in other words, data is sent and received simultaneously by several LEDs and several photodiodes. The system can transmit data at more than 100 Mbit/s and five milliseconds latency.
Modern production technologies in the automobile industry must become more flexible in order to fulfil individual customer requirements.
An international team of scientists has discovered a new way to transfer image information through multimodal fibers with almost no distortion - even if the fiber is bent. The results of the study, to which scientist from the Leibniz-Institute of Photonic Technology Jena (Leibniz IPHT) contributed, were published on 6thJune in the highly-cited journal Physical Review Letters.
Endoscopes allow doctors to see into a patient’s body like through a keyhole. Typically, the images are transmitted via a bundle of several hundreds of optical...
13.06.2018 | Event News
08.06.2018 | Event News
05.06.2018 | Event News
22.06.2018 | Materials Sciences
22.06.2018 | Earth Sciences
22.06.2018 | Life Sciences