Heart valve diseases in advanced age are frequent and require customised therapeutic options. A new development in this field has been used for the first time worldwide at Inselspital, Bern University Hospital. Its Department of Cardiology has now evaluated the first international patient data.
More and more people are fulfilling the wish for an active lifestyle into old age. But the societal trend is proceeding to the detriment of the heart, because use over the course of many years can render the mitral valve (the valve between the left atrium and the left ventricle) leaky.
As a result, the heart has additional work due to the backlog of blood. Shortness of breath and ineffciency come about. Almost ten percent of the population over 75 years of age is affected. The development of safe and gentle treatment options for elderly patients with the shortest possible hospital stay is therefore a crucial challenge of contemporary cardiology.
When open heart surgery is out of the question
The optimal treatment of mitral valve diseases is still open heart surgery. But this major intervention poses a risk for many elderly patients because concomitant diseases often exist. As an alternative, the valve can be treated with a catheter through the groin in a minimally invasive (keyhole) procedure. Today cardiologists insert a clip here that repairs the leaking mitral valve. But the clip cannot be inserted with all patients, especially if the heart valve is severely altered.
A new American reconstruction system now has the potential to remedy this restriction. It also comes into question with such anatomically altered heart valves which could not be treated by means of catheter up to now. Cardiologists hope for a reduction in the number and duration of hospital stays and an improved quality of life for those affected.
First use at Bern University Hospital
The Departments of Cardiology and of Cardiovascular Surgery at Bern University Hospital are internationally renowned in the development of gentle and innovative treatment procedures for patients with heart valve diseases. Due to this reputation the new system was used for the first time worldwide in September 2016 at Inselspital, Bern University Hospital. Seven heart valve centres from five different countries (Germany, Greece, Canada, USA and Switzerland) subsequently verified the safety and feasibility of the procedure among elderly persons.
The evaluation of patient data under the leadership of Prof. Dr. med. Stephan Windecker at Bern University Hospital revealed that the new system can be used reliably among patients who were difficult to treat with available techniques. In addition, it closed the leaking mitral valve very effectively: 95 percent of patients indicated a noticeable improvement of their complaints after the procedure. These promising results will now be confirmed in long-term studies with a larger patient population before the new system can be approved. The initial evaluation was published on 19 August in “The Lancet”.
Prof. Dr. med. Stephan Windecker, Director and Chief Physician, Department of Cardiology, Inselspital, Bern University Hospital, +41 31 63 2 44 97, Stephan.Windecker@insel.ch
Monika Kugemann | Universitätsspital Bern
A first look at interstitial fluid flow in the brain
05.07.2018 | American Institute of Physics
A sentinel to watch over ocular pressure
04.07.2018 | Fraunhofer Institute for Microelectronic Circuits and Systems
A new manufacturing technique uses a process similar to newspaper printing to form smoother and more flexible metals for making ultrafast electronic devices.
The low-cost process, developed by Purdue University researchers, combines tools already used in industry for manufacturing metals on a large scale, but uses...
For the first time ever, scientists have determined the cosmic origin of highest-energy neutrinos. A research group led by IceCube scientist Elisa Resconi, spokesperson of the Collaborative Research Center SFB1258 at the Technical University of Munich (TUM), provides an important piece of evidence that the particles detected by the IceCube neutrino telescope at the South Pole originate from a galaxy four billion light-years away from Earth.
To rule out other origins with certainty, the team led by neutrino physicist Elisa Resconi from the Technical University of Munich and multi-wavelength...
For the first time a team of researchers have discovered two different phases of magnetic skyrmions in a single material. Physicists of the Technical Universities of Munich and Dresden and the University of Cologne can now better study and understand the properties of these magnetic structures, which are important for both basic research and applications.
Whirlpools are an everyday experience in a bath tub: When the water is drained a circular vortex is formed. Typically, such whirls are rather stable. Similar...
Physicists working with Roland Wester at the University of Innsbruck have investigated if and how chemical reactions can be influenced by targeted vibrational excitation of the reactants. They were able to demonstrate that excitation with a laser beam does not affect the efficiency of a chemical exchange reaction and that the excited molecular group acts only as a spectator in the reaction.
A frequently used reaction in organic chemistry is nucleophilic substitution. It plays, for example, an important role in in the synthesis of new chemical...
Optical spectroscopy allows investigating the energy structure and dynamic properties of complex quantum systems. Researchers from the University of Würzburg present two new approaches of coherent two-dimensional spectroscopy.
"Put an excitation into the system and observe how it evolves." According to physicist Professor Tobias Brixner, this is the credo of optical spectroscopy....
13.07.2018 | Event News
12.07.2018 | Event News
03.07.2018 | Event News
23.07.2018 | Health and Medicine
23.07.2018 | Earth Sciences
23.07.2018 | Science Education