Scientists at the University of Gothenburg, Sweden, have discovered that one type of the body’s water channels can be modified such that it becomes more stable , which may be significant in the treatment of several diseases.
“It’s important to understand how the water channels, which are known as ‘aquaporins’, in the body work, since they control many of the processes in our cells and tissues. They also determine what is to be transported into and out of the cell, and they are thus highly significant in the development of new treatments for various diseases, such as eczema, cerebral oedema, obesity and cancer”, says Kristina Hedfalk of the Department of Chemistry at the University of Gothenburg.Aquaporins are vital
The research group, which consists of Fredrik Öberg, Jennie Sjöhamn, Gerhard Fischer, Andreas Moberg, Anders Pedersen, Richard Neutze and Kristina Hedfalk, describes their studies of one of the most recently discovered aquaporins in an article in the scientific journal The Journal of Biological Chemistry. This aquaporin, AQP10, is preferentially found in the intestine, and is particularly interesting since it transports both water and sugar alcohols.Carbohydrates stabilise the water channel
The article Glycosylation Increases the Thermostability of Human Aquaporin 10 Protein has been published in the September edition of The Journal of Biological Chemistry.
Title: Glycosylation Increases the Thermostability of Human Aquaporin 10 ProteinFor more information, please contact: Kristina Hedfalk
Helena Aaberg | idw
Switch-in-a-cell electrifies life
18.12.2018 | Rice University
Plant biologists identify mechanism behind transition from insect to wind pollination
18.12.2018 | University of Toronto
Researchers from the University of Basel have reported a new method that allows the physical state of just a few atoms or molecules within a network to be controlled. It is based on the spontaneous self-organization of molecules into extensive networks with pores about one nanometer in size. In the journal ‘small’, the physicists reported on their investigations, which could be of particular importance for the development of new storage devices.
Around the world, researchers are attempting to shrink data storage devices to achieve as large a storage capacity in as small a space as possible. In almost...
The more objects we make "smart," from watches to entire buildings, the greater the need for these devices to store and retrieve massive amounts of data quickly without consuming too much power.
Millions of new memory cells could be part of a computer chip and provide that speed and energy savings, thanks to the discovery of a previously unobserved...
What if, instead of turning up the thermostat, you could warm up with high-tech, flexible patches sewn into your clothes - while significantly reducing your...
A widely used diabetes medication combined with an antihypertensive drug specifically inhibits tumor growth – this was discovered by researchers from the University of Basel’s Biozentrum two years ago. In a follow-up study, recently published in “Cell Reports”, the scientists report that this drug cocktail induces cancer cell death by switching off their energy supply.
The widely used anti-diabetes drug metformin not only reduces blood sugar but also has an anti-cancer effect. However, the metformin dose commonly used in the...
A research team from the University of Zurich has developed a new drone that can retract its propeller arms in flight and make itself small to fit through narrow gaps and holes. This is particularly useful when searching for victims of natural disasters.
Inspecting a damaged building after an earthquake or during a fire is exactly the kind of job that human rescuers would like drones to do for them. A flying...
12.12.2018 | Event News
10.12.2018 | Event News
06.12.2018 | Event News
18.12.2018 | Materials Sciences
18.12.2018 | Physics and Astronomy
18.12.2018 | Physics and Astronomy