Inconsistencies with Neanderthal Genomic DNA Sequences

Two recent papers describing the sequencing of Neanderthal nuclear DNA from fossil bone held promise for finally answering this question [1, 2]. However, the two studies came to very different conclusions regarding the ancestral role of Neanderthals.

Jeffrey D. Wall and Sung K. Kim from University of California San Francisco now reveal in PLoS Genetics what they found when they reanalyzed the data from the two original studies.

Wall and Kim’s reanalysis reveals inconsistencies between them and they believe that possible contamination with modern human DNA and/or a high rate of sequencing errors compromised the findings of one of the original Neanderthal DNA studies.

The authors therefore recommend that we carefully evaluate published and future data before arriving at any firm conclusions about human evolution.