A stroke is caused when part of the blood supply to the brain is cut off. This causes acidity in the brain to build up, leading to damage.
CT scans are currently used to detect bleeding, swelling and tumours in the brain, but the visibility of soft tissue is very limited, making damage difficult to detect.
Professors Morris and Kauppinen will use advanced Nuclear Magnetic Resonance (NMR) technologies to allow MRI scanners to create detailed images of pH in the brain.
The images will be used to compare healthy (neutral, pH 7) and damaged (acidic, lower pH) areas of the brain, and to measure how the pH of the brain changes over time, with the aim of providing more targeted and effective treatments.
Professor Morris said: “Within two to three years we hope to have developed an NMR technique which can be translated into a machine that can image acidity in the brain.
“If we can map stroke damage accurately, doctors will have a better chance to provide more targeted and effective treatment. Current techniques often only enable one to see damage once it is too late to intervene.”
NMR will be used to measure the rate at which hydrogen ions are exchanged between water and proteins in the brain. Acidity causes this rate to increase, changing the NMR signal of water.
The grant, from the Engineering and Physical Sciences Research Council, will fund three new NMR instruments in the university’s School of Chemistry, which is the second largest university Chemistry department in the UK and one of the largest in Europe. The new instruments will also support a wide range of other developments in organic, inorganic and materials chemistry.
Simon Hunter | alfa
Solving the efficiency of Gram-negative bacteria
22.03.2019 | Harvard University
Bacteria bide their time when antibiotics attack
22.03.2019 | Rice University
DESY and MPSD scientists create high-order harmonics from solids with controlled polarization states, taking advantage of both crystal symmetry and attosecond electronic dynamics. The newly demonstrated technique might find intriguing applications in petahertz electronics and for spectroscopic studies of novel quantum materials.
The nonlinear process of high-order harmonic generation (HHG) in gases is one of the cornerstones of attosecond science (an attosecond is a billionth of a...
Nano- and microtechnology are promising candidates not only for medical applications such as drug delivery but also for the creation of little robots or flexible integrated sensors. Scientists from the Max Planck Institute for Polymer Research (MPI-P) have created magnetic microparticles, with a newly developed method, that could pave the way for building micro-motors or guiding drugs in the human body to a target, like a tumor. The preparation of such structures as well as their remote-control can be regulated using magnetic fields and therefore can find application in an array of domains.
The magnetic properties of a material control how this material responds to the presence of a magnetic field. Iron oxide is the main component of rust but also...
Due to the special arrangement of its molecules, a new coating made of corn starch is able to repair small scratches by itself through heat: The cross-linking via ring-shaped molecules makes the material mobile, so that it compensates for the scratches and these disappear again.
Superficial micro-scratches on the car body or on other high-gloss surfaces are harmless, but annoying. Especially in the luxury segment such surfaces are...
The Potsdam Echelle Polarimetric and Spectroscopic Instrument (PEPSI) at the Large Binocular Telescope (LBT) in Arizona released its first image of the surface magnetic field of another star. In a paper in the European journal Astronomy & Astrophysics, the PEPSI team presents a Zeeman- Doppler-Image of the surface of the magnetically active star II Pegasi.
A special technique allows astronomers to resolve the surfaces of faraway stars. Those are otherwise only seen as point sources, even in the largest telescopes...
Researchers at Chalmers University of Technology and the University of Gothenburg, Sweden, have proposed a way to create a completely new source of radiation. Ultra-intense light pulses consist of the motion of a single wave and can be described as a tsunami of light. The strong wave can be used to study interactions between matter and light in a unique way. Their research is now published in the scientific journal Physical Review Letters.
"This source of radiation lets us look at reality through a new angle - it is like twisting a mirror and discovering something completely different," says...
11.03.2019 | Event News
01.03.2019 | Event News
28.02.2019 | Event News
22.03.2019 | Life Sciences
22.03.2019 | Life Sciences
22.03.2019 | Information Technology