A study published today in the journal Critical Care reveals that a daily variation of C-reactive protein (CRP) levels greater than 4.1 mg/dl is a good marker for prediction of infection. The authors of the study also identify different patterns of CRP level progression, associated with different predictions of infection, which could guide antibiotic prescription.
Pedro Povoa, from Hospital de São Francisco Xavier in Lisbon, Portugal and colleagues from the Hospital Garcia de Orta in Almada, Portugal analysed the CRP levels of patients admitted to their intensive care unit (ICU) during 72 hours or more. Among the patients selected for the study, 35 acquired an infection during their stay at the ICU and 28 did not. Povoa et al. analysed the patients’ records of CRP levels during the five days before diagnosis of infection or ICU discharge, respectively.
Povoa et al. found that a daily variation of CRP levels greater than 4.1 mg/dl is a good marker for prediction of infection, with 92.1% sensitivity and 71.4% specificity. If combined with a CRP concentration greater than 8.7 mg/dl, the prediction power increased even further. Eighty-eight percent of patients with a daily variation of CRP levels greater than 4.1 mg/dl and a CRP concentration greater than 8.7 mg/dl developed an infection. Povoa et al. conclude that monitoring CRP progression could help in clinical decision-making and the prescription of antibiotics.
Juliette Savin | alfa
NYSCF researchers develop novel bioengineering technique for personalized bone grafts
18.07.2018 | New York Stem Cell Foundation
Pollen taxi for bacteria
18.07.2018 | Technische Universität München
For the first time ever, scientists have determined the cosmic origin of highest-energy neutrinos. A research group led by IceCube scientist Elisa Resconi, spokesperson of the Collaborative Research Center SFB1258 at the Technical University of Munich (TUM), provides an important piece of evidence that the particles detected by the IceCube neutrino telescope at the South Pole originate from a galaxy four billion light-years away from Earth.
To rule out other origins with certainty, the team led by neutrino physicist Elisa Resconi from the Technical University of Munich and multi-wavelength...
For the first time a team of researchers have discovered two different phases of magnetic skyrmions in a single material. Physicists of the Technical Universities of Munich and Dresden and the University of Cologne can now better study and understand the properties of these magnetic structures, which are important for both basic research and applications.
Whirlpools are an everyday experience in a bath tub: When the water is drained a circular vortex is formed. Typically, such whirls are rather stable. Similar...
Physicists working with Roland Wester at the University of Innsbruck have investigated if and how chemical reactions can be influenced by targeted vibrational excitation of the reactants. They were able to demonstrate that excitation with a laser beam does not affect the efficiency of a chemical exchange reaction and that the excited molecular group acts only as a spectator in the reaction.
A frequently used reaction in organic chemistry is nucleophilic substitution. It plays, for example, an important role in in the synthesis of new chemical...
Optical spectroscopy allows investigating the energy structure and dynamic properties of complex quantum systems. Researchers from the University of Würzburg present two new approaches of coherent two-dimensional spectroscopy.
"Put an excitation into the system and observe how it evolves." According to physicist Professor Tobias Brixner, this is the credo of optical spectroscopy....
Ultra-short, high-intensity X-ray flashes open the door to the foundations of chemical reactions. Free-electron lasers generate these kinds of pulses, but there is a catch: the pulses vary in duration and energy. An international research team has now presented a solution: Using a ring of 16 detectors and a circularly polarized laser beam, they can determine both factors with attosecond accuracy.
Free-electron lasers (FELs) generate extremely short and intense X-ray flashes. Researchers can use these flashes to resolve structures with diameters on the...
13.07.2018 | Event News
12.07.2018 | Event News
03.07.2018 | Event News
18.07.2018 | Materials Sciences
18.07.2018 | Life Sciences
18.07.2018 | Health and Medicine