Resistance to antibiotics is spreading dangerously among bacteria, some of them being resistant to all known medicine. To face this challenge, a radically novel line of attack consists in disorganizing infections, instead of killing individual bacteria. Just like the coordinated activity of our cells is the basis of the proper functioning of our body, the coordinated activity of bacteria is often the basis of infections’ efficiency, and certain drugs have been shown experimentally to impede this coordination.
In a paper recently published in Ecology Letters, André and Godelle build a mathematical model showing that one of the most interesting advantages of these drugs is that the evolution of bacterial resistance would be orders of magnitude slower than in the case of antibiotics.
The authors suggest an interesting interpretation. When a drug targets global properties of infections, the units of organization potentially resisting that drug are precisely the infections, and not the bacteria. In consequence, instead of facing billions of microscopic individuals the drug is only facing a reduced number of larger organisms (infections) with slower evolutionary rate.
Lynne Miller | alfa
Microscope measures muscle weakness
16.11.2018 | Friedrich-Alexander-Universität Erlangen-Nürnberg
Good preparation is half the digestion
16.11.2018 | Max-Planck-Institut für Stoffwechselforschung
Researchers at the University of New Hampshire have captured a difficult-to-view singular event involving "magnetic reconnection"--the process by which sparse particles and energy around Earth collide producing a quick but mighty explosion--in the Earth's magnetotail, the magnetic environment that trails behind the planet.
Magnetic reconnection has remained a bit of a mystery to scientists. They know it exists and have documented the effects that the energy explosions can...
Biochips have been developed at TU Wien (Vienna), on which tissue can be produced and examined. This allows supplying the tissue with different substances in a very controlled way.
Cultivating human cells in the Petri dish is not a big challenge today. Producing artificial tissue, however, permeated by fine blood vessels, is a much more...
Faster and secure data communication: This is the goal of a new joint project involving physicists from the University of Würzburg. The German Federal Ministry of Education and Research funds the project with 14.8 million euro.
In our digital world data security and secure communication are becoming more and more important. Quantum communication is a promising approach to achieve...
On Saturday, 10 November 2018, the research icebreaker Polarstern will leave its homeport of Bremerhaven, bound for Cape Town, South Africa.
When choosing materials to make something, trade-offs need to be made between a host of properties, such as thickness, stiffness and weight. Depending on the application in question, finding just the right balance is the difference between success and failure
Now, a team of Penn Engineers has demonstrated a new material they call "nanocardboard," an ultrathin equivalent of corrugated paper cardboard. A square...
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16.11.2018 | Health and Medicine
16.11.2018 | Life Sciences
16.11.2018 | Life Sciences