Impaired function of a receptor that regulates release of a mood elevating hormone in the brain may be responsible for causing depression, anxiety and cardiovascular disorders, according to a Yale study in Pharmacogenetics and Genomics.
The genetic variant that causes this malfunction is nearly 15 times as prevalent in African-Americans as Caucasians and might explain why African-Americans have a higher rate of congestive heart failure, according to the first author, Alexander Neumeister, M.D., associate professor in the Department of Psychiatry at Yale School of Medicine.
In his study of 29 healthy African-Americans, 11 had the genetic variant, nine were carriers of the genetic variant, and nine were not carriers. Those who tested positive for the genetic variant had elevated norepinephrine levels, heart rate and blood pressure, suggesting impaired receptor function. The effects were more pronounced after the subjects were given a medication that blocked the action of the receptor, causing a sustained release of norepinephrine.
Jacqueline Weaver | EurekAlert!
New findings help to better calculate the oceans’ contribution to climate regulation
14.11.2018 | Jacobs University Bremen gGmbH
How algae and carbon fibers could sustainably reduce the athmospheric carbon dioxide concentration
14.11.2018 | Technische Universität München
Biochips have been developed at TU Wien (Vienna), on which tissue can be produced and examined. This allows supplying the tissue with different substances in a very controlled way.
Cultivating human cells in the Petri dish is not a big challenge today. Producing artificial tissue, however, permeated by fine blood vessels, is a much more...
Faster and secure data communication: This is the goal of a new joint project involving physicists from the University of Würzburg. The German Federal Ministry of Education and Research funds the project with 14.8 million euro.
In our digital world data security and secure communication are becoming more and more important. Quantum communication is a promising approach to achieve...
On Saturday, 10 November 2018, the research icebreaker Polarstern will leave its homeport of Bremerhaven, bound for Cape Town, South Africa.
When choosing materials to make something, trade-offs need to be made between a host of properties, such as thickness, stiffness and weight. Depending on the application in question, finding just the right balance is the difference between success and failure
Now, a team of Penn Engineers has demonstrated a new material they call "nanocardboard," an ultrathin equivalent of corrugated paper cardboard. A square...
Physicists at ETH Zurich demonstrate how errors that occur during the manipulation of quantum system can be monitored and corrected on the fly
The field of quantum computation has seen tremendous progress in recent years. Bit by bit, quantum devices start to challenge conventional computers, at least...
09.11.2018 | Event News
06.11.2018 | Event News
23.10.2018 | Event News
14.11.2018 | Materials Sciences
14.11.2018 | Health and Medicine
14.11.2018 | Life Sciences