Scientists at The Scripps Research Institute and the Salk Institute for Biological Studies are reporting a possible answer to a longstanding question in research on the origins of life on Earth--how did the first amino acids form the first peptides?
Peptides and proteins are strings of amino acid building blocks, and they are one of the most important classes of biological molecules found in living things today. Fifty years of chemical research on the origins of life has shown that amino acids could have formed spontaneously on the early Earth environment or could have been introduced onto the early Earth from meteorites.
"There are lots of ways to make amino acids," says Professor M. Reza Ghadiri, Ph.D., who is a member of The Skaggs Institute for Chemical Biology at Scripps Research. "But the question is, how do you couple them together?"
Ghadiri and Luke Leman, who is a member of the Kellogg School of Science and Technology at Scripps Research, worked out one possible solution with Leslie Orgel of the Salk Institute. In the latest issue of the journal Science, Leman, Ghadiri, and Orgel suggest that the missing link is a chemical component of volcanic gas known as carbonyl sulfide.
Jason Bardi | EurekAlert!
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