It may be a right-handed world, but recent Purdue University research indicates that the first building blocks of life were lefties – and suggests why, on a molecular level, all living things remain southpaws to this day.
This schematic illustrates Cooks theory of how serine, one of the 20 amino acids that comprise all living things, may have determined the chirality of other biological molecules at the dawn of evolution. "Left-handed" serine, shown here as L-serine, has virtually the same properties as "right-handed" D-serine. But because of an unknown process that possibly caused L-serine to become more prevalent than D-serine in the environment, the strong clusters that L-serine forms bonded only with other left-handed amino acids and right-handed sugars. Other biological molecules with an incompatible chirality were left out of the bonding process, and all the organisms on the planet eventually developed from amino acids with exclusively left-handed chirality.
For higher resolution graphic klick here
In findings that may shed light on the earliest days of evolutionary history, R. Graham Cooks and a team of Purdue chemists have reported experiments that suggest why all 20 of the amino acids that comprise living things exhibit "left-handed chirality," which refers to the direction these basic biological molecules twist–and how a single amino acid might be the reason.
Amino acids can be oriented either to the left or the right and possess the same chemical properties regardless of their chirality. But somewhere along the line, living things evolved using only amino acids of the left-handed variety. Scientists have puzzled over the reason for many years, but Cooks’ group seems to have found the answer: A single amino acid called serine set the standard eons ago, forcing all other biological molecules to follow suit.
Chad Boutin | Purdue University
Colorectal cancer: Increased life expectancy thanks to individualised therapies
20.02.2020 | Christian-Albrechts-Universität zu Kiel
Sweet beaks: What Galapagos finches and marine bacteria have in common
20.02.2020 | Max-Planck-Institut für Marine Mikrobiologie
The operational speed of semiconductors in various electronic and optoelectronic devices is limited to several gigahertz (a billion oscillations per second). This constrains the upper limit of the operational speed of computing. Now researchers from the Max Planck Institute for the Structure and Dynamics of Matter in Hamburg, Germany, and the Indian Institute of Technology in Bombay have explained how these processes can be sped up through the use of light waves and defected solid materials.
Light waves perform several hundred trillion oscillations per second. Hence, it is natural to envision employing light oscillations to drive the electronic...
Most natural and artificial surfaces are rough: metals and even glasses that appear smooth to the naked eye can look like jagged mountain ranges under the microscope. There is currently no uniform theory about the origin of this roughness despite it being observed on all scales, from the atomic to the tectonic. Scientists suspect that the rough surface is formed by irreversible plastic deformation that occurs in many processes of mechanical machining of components such as milling.
Prof. Dr. Lars Pastewka from the Simulation group at the Department of Microsystems Engineering at the University of Freiburg and his team have simulated such...
Investigation of the temperature dependence of the skyrmion Hall effect reveals further insights into possible new data storage devices
The joint research project of Johannes Gutenberg University Mainz (JGU) and the Massachusetts Institute of Technology (MIT) that had previously demonstrated...
Researchers at Chalmers University of Technology, Sweden, recently completed a 5-year research project looking at how to make fibre optic communications systems more energy efficient. Among their proposals are smart, error-correcting data chip circuits, which they refined to be 10 times less energy consumptive. The project has yielded several scientific articles, in publications including Nature Communications.
Streaming films and music, scrolling through social media, and using cloud-based storage services are everyday activities now.
After helping develop a new approach for organic synthesis -- carbon-hydrogen functionalization -- scientists at Emory University are now showing how this approach may apply to drug discovery. Nature Catalysis published their most recent work -- a streamlined process for making a three-dimensional scaffold of keen interest to the pharmaceutical industry.
"Our tools open up whole new chemical space for potential drug targets," says Huw Davies, Emory professor of organic chemistry and senior author of the paper.
12.02.2020 | Event News
16.01.2020 | Event News
15.01.2020 | Event News
21.02.2020 | Medical Engineering
21.02.2020 | Health and Medicine
21.02.2020 | Physics and Astronomy