The bacterium that commonly causes stomach ulcers in humans is called Helicobacter pylori. Extensive research has been carried out on this bacterium and the two scientists who discovered it were awarded the Nobel Prize for Physiology and Medicine in 2005. However, in a small percentage of biopsies a similar but previously unidentified bacterium is present. Numerous research papers have described failed attempts to culture this microbe in the laboratory since it was first observed in 1990. Now, scientists from Belgium have succeeded.
"We have developed a new method to cultivate these bacteria and can now study their main characteristics and virulence properties," said Professor Dr Freddy Haesebrouck from Gent University in Belgium. The researchers had to recreate aspects of the bacterium's natural habitat, the stomach. They used acid, which kills other microbes but is needed for these bacteria to grow. Charcoal was used to remove substances that are toxic to the stomach bacterium. Genetic analysis revealed that it is a new species related to the common stomach ulcer bacterium Helicobacter pylori. Its name, Helicobacter suis, comes from the Latin for "of the pig".
H. suis has been associated with stomach ulcers in pigs, which may cause sudden death: a big problem for farmers. "The economic losses for the pork industry and the risk of the bacteria infecting humans justify the need for further research," said Dr Margo Baele from Gent University in Belgium. "Data shows that people in close contact with pigs have a higher risk of infection; this suggests H. suis is a zoonotic agent, capable of being transmitted from animals to humans."
"We know very little about how the bacterium infects humans and pigs and how it causes disease. Thanks to this research, pure isolates of H. suis are now available, bringing new perspectives to the study of this organism and its interaction with the host," says Professor Dr Freddy Haesebrouck.
The new technique will allow researchers to determine whether the bacterium is resistant to antibiotics. This will lead to better treatment strategies, both in pigs and humans. The researchers hope it may also result in the development of an effective vaccine.
Lucy Goodchild | alfa
Turning carbon dioxide into liquid fuel
06.08.2020 | DOE/Argonne National Laboratory
Tellurium makes the difference
06.08.2020 | Friedrich-Schiller-Universität Jena
Scientists at the Fraunhofer Institute for Laser Technology ILT have come up with a striking new addition to contact stamping technologies in the ERDF research project ScanCut. In collaboration with industry partners from North Rhine-Westphalia, the Aachen-based team of researchers developed a hybrid manufacturing process for the laser cutting of thin-walled metal strips. This new process makes it possible to fabricate even the tiniest details of contact parts in an eco-friendly, high-precision and efficient manner.
Plug connectors are tiny and, at first glance, unremarkable – yet modern vehicles would be unable to function without them. Several thousand plug connectors...
An international research team has found a new approach that may be able to reduce bone loss in osteoporosis and maintain bone health.
Osteoporosis is the most common age-related bone disease which affects hundreds of millions of individuals worldwide. It is estimated that one in three women...
Traditional single-cell sequencing methods help to reveal insights about cellular differences and functions - but they do this with static snapshots only...
“Core-shell” clusters pave the way for new efficient nanomaterials that make catalysts, magnetic and laser sensors or measuring devices for detecting electromagnetic radiation more efficient.
Whether in innovative high-tech materials, more powerful computer chips, pharmaceuticals or in the field of renewable energies, nanoparticles – smallest...
An international research team with Prof. Cornelia Denz from the Institute of Applied Physics at the University of Münster develop for the first time light fields using caustics that do not change during propagation. With the new method, the physicists cleverly exploit light structures that can be seen in rainbows or when light is transmitted through drinking glasses.
Modern applications as high resolution microsopy or micro- or nanoscale material processing require customized laser beams that do not change during...
23.07.2020 | Event News
21.07.2020 | Event News
07.07.2020 | Event News
06.08.2020 | Earth Sciences
06.08.2020 | Power and Electrical Engineering
06.08.2020 | Life Sciences