Over one thousand people in Northern Ireland have been involved in the study carried out by Dr Tony O’Neill from the School of Medicine and Dentistry and two professors from Virginia Commonwealth University.
It typically starts in late adolescence, and can have a devastating effect on sufferers and carers.
The discovery of the gene, MEGF10, which is associated with severe schizophrenia, could be a step in the right direction towards helping those affected.
The study found abnormally high levels of the gene in a region of the brain previously shown to be linked to the condition by Dr O’Neill and his colleagues.
Dr O’Neill, from the Department of Psychiatry at Queen’s, said: “This further finding helps piece together the complex picture underlying risk to schizophrenia and offers the hope of more successful interventions in the future.
“We are beginning to understand how difficulties with the developing brain can compromise important brain systems leading to the bewildering and distressful symptoms of schizophrenia. It is a really exciting time for psychiatric research.”
The study is the latest in a series of publications resulting from a 20 year collaboration between Queen’s and Virginia Commonwealth University.
The group was the first to identify Dysbindin, the first risk gene for schizophrenia. That finding was described as the most important in psychiatry for 20 years and was replicated in many other populations.
Lisa Mitchell | alfa
Family of crop viruses revealed at high resolution for the first time
15.10.2019 | John Innes Centre
Receptor complexes on the assembly line
15.10.2019 | Albert-Ludwigs-Universität Freiburg im Breisgau
Researchers at Ludwig-Maximilians-Universitaet (LMU) in Munich have explored the initial consequences of the interaction of light with molecules on the surface of nanoscopic aerosols.
The nanocosmos is constantly in motion. All natural processes are ultimately determined by the interplay between radiation and matter. Light strikes particles...
Particles that are mere nanometers in size are at the forefront of scientific research today. They come in many different shapes: rods, spheres, cubes, vesicles, S-shaped worms and even donut-like rings. What makes them worthy of scientific study is that, being so tiny, they exhibit quantum mechanical properties not possible with larger objects.
Researchers at the Center for Nanoscale Materials (CNM), a U.S. Department of Energy (DOE) Office of Science User Facility located at DOE's Argonne National...
A new research project at the TH Mittelhessen focusses on the development of a novel light weight design concept for leisure boats and yachts. Professor Stephan Marzi from the THM Institute of Mechanics and Materials collaborates with Krake Catamarane, which is a shipyard located in Apolda, Thuringia.
The project is set up in an international cooperation with Professor Anders Biel from Karlstad University in Sweden and the Swedish company Lamera from...
Superconductivity has fascinated scientists for many years since it offers the potential to revolutionize current technologies. Materials only become superconductors - meaning that electrons can travel in them with no resistance - at very low temperatures. These days, this unique zero resistance superconductivity is commonly found in a number of technologies, such as magnetic resonance imaging (MRI).
Future technologies, however, will harness the total synchrony of electronic behavior in superconductors - a property called the phase. There is currently a...
How do some neutron stars become the strongest magnets in the Universe? A German-British team of astrophysicists has found a possible answer to the question of how these so-called magnetars form. Researchers from Heidelberg, Garching, and Oxford used large computer simulations to demonstrate how the merger of two stars creates strong magnetic fields. If such stars explode in supernovae, magnetars could result.
How Do the Strongest Magnets in the Universe Form?
02.10.2019 | Event News
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15.10.2019 | Life Sciences