Led by researchers at the University of Maryland School of Pharmacy, the mouse study may be ideal, they say, for testing new obesity controlling drugs and studies of the condition itself.
In the Dec. 13 online issue of the International Journal of Obesity, Wanli Smith, PhD, assistant professor in the Department of Pharmaceutical Sciences, and colleagues report a link between the protein synphilin-1 and obesity.
The School of Pharmacy researchers are collaborating with University of Maryland School of Medicine researchers to confirm if obese humans also express more synphilin-1 than others. Also, they are seeking collaboration with pharmaceutical companies.
“We have a new functional model that no one has done before,” says Smith. She explains that the pathogenesis of obesity is not fully understood by scientists. The mice also displayed some effects on high insulin levels and impaired glucose tolerance. Exploring the role of novel proteins in obesity may provide important insights into its causes and treatments.
The report pinpoints a previously unidentified role for synphilin-1 in controlling body weight. Synphilin-1 is a protein in cell plasma that was earlier shown to have implications with Parkinson’s disease symptoms. The University of Maryland team and others demonstrated recently that synphilin-1 may have protection effects in Parkinson’s disease models.
Steve Berberich | Newswise Science News
Microscope measures muscle weakness
16.11.2018 | Friedrich-Alexander-Universität Erlangen-Nürnberg
Good preparation is half the digestion
16.11.2018 | Max-Planck-Institut für Stoffwechselforschung
Researchers at the University of New Hampshire have captured a difficult-to-view singular event involving "magnetic reconnection"--the process by which sparse particles and energy around Earth collide producing a quick but mighty explosion--in the Earth's magnetotail, the magnetic environment that trails behind the planet.
Magnetic reconnection has remained a bit of a mystery to scientists. They know it exists and have documented the effects that the energy explosions can...
Biochips have been developed at TU Wien (Vienna), on which tissue can be produced and examined. This allows supplying the tissue with different substances in a very controlled way.
Cultivating human cells in the Petri dish is not a big challenge today. Producing artificial tissue, however, permeated by fine blood vessels, is a much more...
Faster and secure data communication: This is the goal of a new joint project involving physicists from the University of Würzburg. The German Federal Ministry of Education and Research funds the project with 14.8 million euro.
In our digital world data security and secure communication are becoming more and more important. Quantum communication is a promising approach to achieve...
On Saturday, 10 November 2018, the research icebreaker Polarstern will leave its homeport of Bremerhaven, bound for Cape Town, South Africa.
When choosing materials to make something, trade-offs need to be made between a host of properties, such as thickness, stiffness and weight. Depending on the application in question, finding just the right balance is the difference between success and failure
Now, a team of Penn Engineers has demonstrated a new material they call "nanocardboard," an ultrathin equivalent of corrugated paper cardboard. A square...
09.11.2018 | Event News
06.11.2018 | Event News
23.10.2018 | Event News
16.11.2018 | Health and Medicine
16.11.2018 | Life Sciences
16.11.2018 | Life Sciences