Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Internet addiction -- Causes at the molecular level

30.08.2012
Researchers from the University of Bonn and the ZI Mannheim find higher frequency of a CHRNA4 gene variation

"It was shown that Internet addiction is not a figment of our imagination," says the lead author, Privatdozent Dr. Christian Montag from the Department for Differential and Biological Psychology at the University of Bonn. "Researchers and therapists are increasingly closing in on it."

Over the past years, the Bonn researchers have interviewed a total of 843 people about their Internet habits. An analysis of the questionnaires shows that 132 men and women in this group exhibit problematic behavior in how they handle the online medium; all their thoughts revolve around the Internet during the day, and they feel their wellbeing is severely impacted if they have to go without it.

Gene variation more frequent in Internet addicts

The researchers from the University of Bonn and the Central Institute of Mental Health in Mannheim compared the genetic makeup of the pro­blematic Internet users with that of healthy control individuals. This showed that the 132 subjects are more often carriers of a genetic variation that also plays a major role in nicotine addiction. "What we already know about the nicotinic acetylcholine receptor in the brain is that a mutation on the related gene promotes addictive behavior," explains Dr. Montag. Nicotine from tobacco fits - just like acetylcholine, which is produced by the body - like a key into this receptor. Both these neurotransmitters play a significant role in activating the brain's reward system. "It seems that this connection is not only essential for nicotine addiction, but also for Internet addiction," reports the Bonn psychologist.

Women more affected by this mutation

The actual mutation is on the CHRNA4 gene that changes the genetic make¬up for the Alpha 4 subunit on the nicotinic acetylcholine receptor. "Within the group of subjects exhibiting problematic Internet behavior this variant occurs more frequently – in particular, in women," says Dr. Montag. This finding will have to be validated further because numerous surveys have found that men are more prone to Internet addiction than women. The psychologist assumes, "The sex-specific genetic finding may result from a specific subgroup of Internet dependency, such as the use of social networks or such."

Better addiction diagnosis through biological markers

Dr. Montag added that studies including more subjects are required to further analyze the connection between this mutation and Internet addiction. "But the current data already shows that there are clear indications for genetic causes of Internet addiction." He added that with the mutation, a biological marker had been found that would allow to characterize online addiction from a neuro-scientific angle. "If such connections are better understood, this will also result in important indications for better therapies," says Dr. Montag.

Publication: The role of the CHRNA4 Gene in Internet Addiction – A Case-control Study, "Journal of Addiction Medicine," DOI: 10.1097/ADM.0b013e31825ba7e7, Internet: http://www.ncbi.nlm.nih.gov/pubmed?term=internet%20addiction%20chrna4

Christian Montag | EurekAlert!
Further information:
http://www.uni-bonn.de

More articles from Life Sciences:

nachricht Climate Impact Research in Hannover: Small Plants against Large Waves
17.08.2018 | Leibniz Universität Hannover

nachricht First transcription atlas of all wheat genes expands prospects for research and cultivation
17.08.2018 | Leibniz-Institut für Pflanzengenetik und Kulturpflanzenforschung

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Color effects from transparent 3D-printed nanostructures

New design tool automatically creates nanostructure 3D-print templates for user-given colors
Scientists present work at prestigious SIGGRAPH conference

Most of the objects we see are colored by pigments, but using pigments has disadvantages: such colors can fade, industrial pigments are often toxic, and...

Im Focus: Unraveling the nature of 'whistlers' from space in the lab

A new study sheds light on how ultralow frequency radio waves and plasmas interact

Scientists at the University of California, Los Angeles present new research on a curious cosmic phenomenon known as "whistlers" -- very low frequency packets...

Im Focus: New interactive machine learning tool makes car designs more aerodynamic

Scientists develop first tool to use machine learning methods to compute flow around interactively designable 3D objects. Tool will be presented at this year’s prestigious SIGGRAPH conference.

When engineers or designers want to test the aerodynamic properties of the newly designed shape of a car, airplane, or other object, they would normally model...

Im Focus: Robots as 'pump attendants': TU Graz develops robot-controlled rapid charging system for e-vehicles

Researchers from TU Graz and their industry partners have unveiled a world first: the prototype of a robot-controlled, high-speed combined charging system (CCS) for electric vehicles that enables series charging of cars in various parking positions.

Global demand for electric vehicles is forecast to rise sharply: by 2025, the number of new vehicle registrations is expected to reach 25 million per year....

Im Focus: The “TRiC” to folding actin

Proteins must be folded correctly to fulfill their molecular functions in cells. Molecular assistants called chaperones help proteins exploit their inbuilt folding potential and reach the correct three-dimensional structure. Researchers at the Max Planck Institute of Biochemistry (MPIB) have demonstrated that actin, the most abundant protein in higher developed cells, does not have the inbuilt potential to fold and instead requires special assistance to fold into its active state. The chaperone TRiC uses a previously undescribed mechanism to perform actin folding. The study was recently published in the journal Cell.

Actin is the most abundant protein in highly developed cells and has diverse functions in processes like cell stabilization, cell division and muscle...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

LaserForum 2018 deals with 3D production of components

17.08.2018 | Event News

Within reach of the Universe

08.08.2018 | Event News

A journey through the history of microscopy – new exhibition opens at the MDC

27.07.2018 | Event News

 
Latest News

Smallest transistor worldwide switches current with a single atom in solid electrolyte

17.08.2018 | Physics and Astronomy

Robots as Tools and Partners in Rehabilitation

17.08.2018 | Information Technology

Climate Impact Research in Hannover: Small Plants against Large Waves

17.08.2018 | Life Sciences

VideoLinks
Science & Research
Overview of more VideoLinks >>>