Bruce Branchini and colleagues describe a need for new medical imaging agents that emit near-infrared light — the light rays that “night vision” technology detects, enabling soldiers to see in the dark. Those rays penetrate deeper into the body and could give doctors a better way of detecting the proteins involved in blood clotting. Scientists already use luciferase, the enzyme that makes lightning bugs glow, in laboratory research.
The new study describes an advance toward using luciferase in medical imaging. The scientists combined a protein obtained from firefly luciferase with a special dye that allows the protein to emit near-infrared light. In laboratory experiments, the new material successfully detected minute amounts of a specific blood protein, called factor Xa, which is used to monitor the effectiveness of heparin treatment. It offers promise for improved monitoring of heparin therapy, the article suggests.
The authors acknowledge funding from the Air Force Office of Scientific Research, the National Science Foundation, and the Hans & Ella McCollum ’21 Vahlteich Endowment.
Michael Woods | Newswise Science News
Scientists uncover the role of a protein in production & survival of myelin-forming cells
19.07.2018 | Advanced Science Research Center, GC/CUNY
NYSCF researchers develop novel bioengineering technique for personalized bone grafts
18.07.2018 | New York Stem Cell Foundation
A new manufacturing technique uses a process similar to newspaper printing to form smoother and more flexible metals for making ultrafast electronic devices.
The low-cost process, developed by Purdue University researchers, combines tools already used in industry for manufacturing metals on a large scale, but uses...
For the first time ever, scientists have determined the cosmic origin of highest-energy neutrinos. A research group led by IceCube scientist Elisa Resconi, spokesperson of the Collaborative Research Center SFB1258 at the Technical University of Munich (TUM), provides an important piece of evidence that the particles detected by the IceCube neutrino telescope at the South Pole originate from a galaxy four billion light-years away from Earth.
To rule out other origins with certainty, the team led by neutrino physicist Elisa Resconi from the Technical University of Munich and multi-wavelength...
For the first time a team of researchers have discovered two different phases of magnetic skyrmions in a single material. Physicists of the Technical Universities of Munich and Dresden and the University of Cologne can now better study and understand the properties of these magnetic structures, which are important for both basic research and applications.
Whirlpools are an everyday experience in a bath tub: When the water is drained a circular vortex is formed. Typically, such whirls are rather stable. Similar...
Physicists working with Roland Wester at the University of Innsbruck have investigated if and how chemical reactions can be influenced by targeted vibrational excitation of the reactants. They were able to demonstrate that excitation with a laser beam does not affect the efficiency of a chemical exchange reaction and that the excited molecular group acts only as a spectator in the reaction.
A frequently used reaction in organic chemistry is nucleophilic substitution. It plays, for example, an important role in in the synthesis of new chemical...
Optical spectroscopy allows investigating the energy structure and dynamic properties of complex quantum systems. Researchers from the University of Würzburg present two new approaches of coherent two-dimensional spectroscopy.
"Put an excitation into the system and observe how it evolves." According to physicist Professor Tobias Brixner, this is the credo of optical spectroscopy....
13.07.2018 | Event News
12.07.2018 | Event News
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20.07.2018 | Power and Electrical Engineering
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20.07.2018 | Materials Sciences