Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Evolution of staph 'superbug' traced between humans and food animals

21.02.2012
A strain of the potentially deadly antibiotic-resistant bacterium known as MRSA has jumped from food animals to humans, according to a new study involving two Northern Arizona University researchers.
Paul Keim, Regents’ professor and director of NAU’s Center for Microbial Genetics and Genomics, and Lance Price, NAU faculty member and director of the Center for Food Microbiology and Environmental Health at the Translational Genomics Research Institute, collaborated with scientists at 20 institutions around the world on the study published today in the online journal mBio.

The TGen-led research utilized whole genome sequencing to study 89 genomes from humans and animals — including turkeys, chickens and pigs — with samples from 19 countries on four continents.

The research focused on methicillin-resistant Staphylococcus aureus CC398, also known as pig MRSA or livestock-associated MRSA because it most often infects people with direct exposure to swine or other food animals. It is likely that MRSA CC398 started as an antibiotic-susceptible strain in humans before it jumped to food animals.

After transferring to food animals, MRSA CC398 became resistant to two important antibiotics, tetracycline and methicillin, which are used for treating staph infections. The resistance likely is a result of the routine antibiotic use that characterizes modern food-animal production. The animals commonly are given antibiotics to prevent infection and promote growth.

Keim, who also serves as director of TGen’s Pathogenic Genomics Division, said the study describes evolution in action. "The most powerful force in evolution is selection. And in this case, humans have supplied a strong force through the excessive use of antibiotic drugs in farm animal production. It is that inappropriate use of antibiotics that is now coming back to haunt us.”

Price, the study’s lead author, said the research was “like watching the birth of a superbug—it is simultaneously fascinating and disconcerting.” He said that while this strain of MRSA was discovered less than a decade ago it appears to be spreading very quickly.

“Our findings underscore the potential public health risks of widespread antibiotic use in food animal production,” Price said. “Staph thrives in crowded and unsanitary conditions. Add antibiotics to that environment and you’re going to create a public health problem.”

CONTACTS:

Cynthia Brown
NAU Office of Public Affairs
928-523-0611
cynthia.brown@nau.edu
Steve Yozwiak
TGen Senior Science Writer
602-343-8704
syozwiak@tgen.org

Cynthia Brown | EurekAlert!
Further information:
http://www.nau.edu

Further reports about: Evolution MRSA antibiotic drug antibiotic use public health

More articles from Life Sciences:

nachricht Nonstop Tranport of Cargo in Nanomachines
20.11.2018 | Max-Planck-Institut für molekulare Zellbiologie und Genetik

nachricht Researchers find social cultures in chimpanzees
20.11.2018 | Universität Leipzig

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Nonstop Tranport of Cargo in Nanomachines

Max Planck researchers revel the nano-structure of molecular trains and the reason for smooth transport in cellular antennas.

Moving around, sensing the extracellular environment, and signaling to other cells are important for a cell to function properly. Responsible for those tasks...

Im Focus: UNH scientists help provide first-ever views of elusive energy explosion

Researchers at the University of New Hampshire have captured a difficult-to-view singular event involving "magnetic reconnection"--the process by which sparse particles and energy around Earth collide producing a quick but mighty explosion--in the Earth's magnetotail, the magnetic environment that trails behind the planet.

Magnetic reconnection has remained a bit of a mystery to scientists. They know it exists and have documented the effects that the energy explosions can...

Im Focus: A Chip with Blood Vessels

Biochips have been developed at TU Wien (Vienna), on which tissue can be produced and examined. This allows supplying the tissue with different substances in a very controlled way.

Cultivating human cells in the Petri dish is not a big challenge today. Producing artificial tissue, however, permeated by fine blood vessels, is a much more...

Im Focus: A Leap Into Quantum Technology

Faster and secure data communication: This is the goal of a new joint project involving physicists from the University of Würzburg. The German Federal Ministry of Education and Research funds the project with 14.8 million euro.

In our digital world data security and secure communication are becoming more and more important. Quantum communication is a promising approach to achieve...

Im Focus: Research icebreaker Polarstern begins the Antarctic season

What does it look like below the ice shelf of the calved massive iceberg A68?

On Saturday, 10 November 2018, the research icebreaker Polarstern will leave its homeport of Bremerhaven, bound for Cape Town, South Africa.

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

Optical Coherence Tomography: German-Japanese Research Alliance hosted Medical Imaging Conference

19.11.2018 | Event News

“3rd Conference on Laser Polishing – LaP 2018” Attracts International Experts and Users

09.11.2018 | Event News

On the brain’s ability to find the right direction

06.11.2018 | Event News

 
Latest News

Sustainable energy supply in developing and emerging countries: What are the needs?

21.11.2018 | Power and Electrical Engineering

Nonstop Tranport of Cargo in Nanomachines

20.11.2018 | Life Sciences

Researchers find social cultures in chimpanzees

20.11.2018 | Life Sciences

VideoLinks
Science & Research
Overview of more VideoLinks >>>