Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

California Stem Cell Agency Awards $3.4M Grant to the Jackson Laboratory

24.06.2009
The Jackson Laboratory has received a $3.4 million grant from the California Institute for Regenerative Medicine (CIRM), the state’s stem cell agency, to develop new mouse models of human disease that can be used to test innovative stem cell treatments.

The Jackson Laboratory has received a $3.4 million grant from the California Institute for Regenerative Medicine (CIRM), the state’s stem cell agency, to help speed the development of new therapies for cancer, Alzheimer’s, Parkinson’s and other diseases.

The nonprofit Jackson Laboratory, based in Bar Harbor, has a facility in Sacramento that provides research services to the West Coast biomedical community. The Jackson Laboratory—West will use the CIRM grant to develop new mouse models of human disease that can be used to test innovative stem cell treatments.

Jackson Laboratory President and CEO Rick Woychik, Ph.D., says, “Stem cells have tremendous potential for treating human diseases because of their unique capacity to develop into any cell type in the body. However, before stem cell therapies are used in human patients, it is critical to test their efficacy and safety using a research animal that has the relevant disease.”

The laboratory mouse, widely recognized as the premier mammalian model for studying human disease, is the optimal organism for these preclinical studies, Woychik says.

CIRM issued the award as part of a $40.6 million package of new and continuing grants to California universities and public and private research laboratories. The Jackson project is among those CIRM describes as “early translational” and “intended to either lead to a drug candidate for an unmet medical need or address a bottleneck in the development of new therapies.”

Woychik notes that the grant illustrates the value of having established a presence for the Laboratory in California. “Being located in the world’s largest biomedical research community brings us opportunities that would otherwise be unavailable to us,” he says. “This grant, like more than 90 percent of our funding, comes from outside Maine.”

Leon Hall, Ph.D., is a program director of The Jackson Laboratory—West group that will develop the new mouse models. While mouse models are available for a wide range of human diseases, Hall says, “The Jackson Laboratory now has immune-deficient mice that support long-term transplantation with human stem cells. This grant will allow us to develop new and more relevant mouse models of disease that can sustain human stem cell engraftment. This should eliminate a major barrier to the translation of basic stem cell research to the clinic.”

Chuck Hewett, Ph.D., Jackson VP and chief operating officer, added that “once these new models are developed, The Jackson Laboratory—West will use its new, state-of-the-art facilities to ensure efficient delivery of these mice within California and to provide services to stem cell investigators to reveal information about disease progression.”

The Jackson Laboratory established JAX—West at a small facility in West Sacramento in 2001. In late 2008 JAX—West moved to a larger facility in Sacramento, with about 85 employees on site. Providing a pathogen-free environment for the laboratory animals, the facility meets the highest federal, state and voluntary standards for animal care, genetic quality control and health status, Hewett notes.

Joyce Peterson | Newswise Science News
Further information:
http://www.jax.org

Further reports about: CIRM Laboratory Medicine Stem cell innovation cell death human diseases mouse model

More articles from Awards Funding:

nachricht Ultrasound Connects
13.11.2018 | Albert-Ludwigs-Universität Freiburg im Breisgau

nachricht Improving the understanding of death receptor functions in cells
07.11.2018 | Goethe-Universität Frankfurt am Main

All articles from Awards Funding >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Researchers develop method to transfer entire 2D circuits to any smooth surface

What if a sensor sensing a thing could be part of the thing itself? Rice University engineers believe they have a two-dimensional solution to do just that.

Rice engineers led by materials scientists Pulickel Ajayan and Jun Lou have developed a method to make atom-flat sensors that seamlessly integrate with devices...

Im Focus: Three components on one chip

Scientists at the University of Stuttgart and the Karlsruhe Institute of Technology (KIT) succeed in important further development on the way to quantum Computers.

Quantum computers one day should be able to solve certain computing problems much faster than a classical computer. One of the most promising approaches is...

Im Focus: Substitute for rare earth metal oxides

New Project SNAPSTER: Novel luminescent materials by encapsulating phosphorescent metal clusters with organic liquid crystals

Nowadays energy conversion in lighting and optoelectronic devices requires the use of rare earth oxides.

Im Focus: A bit of a stretch... material that thickens as it's pulled

Scientists have discovered the first synthetic material that becomes thicker - at the molecular level - as it is stretched.

Researchers led by Dr Devesh Mistry from the University of Leeds discovered a new non-porous material that has unique and inherent "auxetic" stretching...

Im Focus: The force of the vacuum

Scientists from the Theory Department of the Max Planck Institute for the Structure and Dynamics of Matter (MPSD) at the Center for Free-Electron Laser Science (CFEL) in Hamburg have shown through theoretical calculations and computer simulations that the force between electrons and lattice distortions in an atomically thin two-dimensional superconductor can be controlled with virtual photons. This could aid the development of new superconductors for energy-saving devices and many other technical applications.

The vacuum is not empty. It may sound like magic to laypeople but it has occupied physicists since the birth of quantum mechanics.

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

New Plastics Economy Investor Forum - Meeting Point for Innovations

10.12.2018 | Event News

EGU 2019 meeting: Media registration now open

06.12.2018 | Event News

Expert Panel on the Future of HPC in Engineering

03.12.2018 | Event News

 
Latest News

Small but ver­sat­ile; key play­ers in the mar­ine ni­tro­gen cycle can util­ize cy­anate and urea

10.12.2018 | Life Sciences

New method gives microscope a boost in resolution

10.12.2018 | Physics and Astronomy

Carnegie Mellon researchers probe hydrogen bonds using new technique

10.12.2018 | Life Sciences

VideoLinks
Science & Research
Overview of more VideoLinks >>>