Adult heart muscle is the least regenerative of human tissues. But embryonic cardiomyocytes (cardiac muscle cells) can multiply, with embryonic stem cells providing an endless reservoir for new cardiac tissue.
In this study, the UCLA team examined the role of matrix elasticity on cardiac muscle development using mouse and human embryonic stem cells, which were grown on different substrates of a silicon-based organic polymer that varied in stiffness. The team found that rigid matrices promoted the generation of more cardiomyocytes cells from ES cells. In addition, ES-derived cardiomyocytes displayed functional maturity and synchronization of beating when cultured with cardiomyocytes harvested from a developing embryo.
Further reports about: > Advanced Investigator Grant > Advanced Materials > Molecular Target > UCLA > adult stem cell > cardiac muscle > cell death > embryonic stem > embryonic stem cell > heart muscle > human embryonic stem cell > human tissue > information technology > living organism > stem cells
Barely scratching the surface: A new way to make robust membranes
13.12.2018 | DOE/Argonne National Laboratory
Topological material switched off and on for the first time
11.12.2018 | ARC Centre of Excellence in Future Low-Energy Electronics Technologies
What if, instead of turning up the thermostat, you could warm up with high-tech, flexible patches sewn into your clothes - while significantly reducing your...
A widely used diabetes medication combined with an antihypertensive drug specifically inhibits tumor growth – this was discovered by researchers from the University of Basel’s Biozentrum two years ago. In a follow-up study, recently published in “Cell Reports”, the scientists report that this drug cocktail induces cancer cell death by switching off their energy supply.
The widely used anti-diabetes drug metformin not only reduces blood sugar but also has an anti-cancer effect. However, the metformin dose commonly used in the...
A research team from the University of Zurich has developed a new drone that can retract its propeller arms in flight and make itself small to fit through narrow gaps and holes. This is particularly useful when searching for victims of natural disasters.
Inspecting a damaged building after an earthquake or during a fire is exactly the kind of job that human rescuers would like drones to do for them. A flying...
Over the last decade, there has been much excitement about the discovery, recognised by the Nobel Prize in Physics only two years ago, that there are two types...
What if a sensor sensing a thing could be part of the thing itself? Rice University engineers believe they have a two-dimensional solution to do just that.
Rice engineers led by materials scientists Pulickel Ajayan and Jun Lou have developed a method to make atom-flat sensors that seamlessly integrate with devices...
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