Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Making plastic smarter with protein

24.03.2003


How do you improve on plastic, a modern material that has already changed the way we do everything from design medical devices to build cars? Embed it with specialized proteins called enzymes, says Shekhar Garde, assistant professor of chemical engineering at Rensselaer Polytechnic Institute.

"Such protein-enhanced plastics might someday be able to act as ultra-hygienic surfaces or sensors to detect the presence of various chemicals," says Garde. These types of materials could have a wide range of applications, for example, in the security or medical industries.

Proteins require water to function, however. Nonwatery environments do not provide the driving force necessary to keep proteins in their normally intricately folded state; unfolded, the molecules cease to function. To learn what it takes to successfully integrate proteins into a dry substance such as plastic, Garde and his graduate student Lu Yang use molecular dynamics (MD) simulations to create a computer model of the proteins and study the molecules in both watery and non-watery environments such as organic solvents. They are working in collaboration with Jonathan S. Dordick, the Howard P. Isermann ’42 Professor of Chemical Engineering, who conducted the initial protein research.



Garde and Yang are presenting their research at the 225th national meeting of the American Chemical Society, held March 23-27 in New Orleans, La.

Proteins Are Powerful, but Sensitive

Proteins are "molecular machines," according to Garde, uniquely able to efficiently and reliably conduct chemical processes. Their powerful activity, however, is limited to relatively low temperatures and pressures. Helping proteins adapt to a non-water-based environment may actually increase the resiliency of the molecules and make them useful in situations they otherwise would not survive in, such as exposure to high temperatures or other extreme conditions. In addition to preserving protein’s known actions, the researchers speculate that they may also "discover that proteins could perform some new functions [in dry environments], something that they could not do in water," according to Yang.


CONTACT: Jonathan Dordick 518-276-2899; dordick@rpi.edu Shekhar Garde 518-276-6048; gardes@rpi.edu

CONTACT (During the ACS meeting): The ACS press room 504-586-4650 (Morial Convention Center, room 280)


Joely Johnson | EurekAlert!
Further information:
http://www.rpi.edu/dept/NewsComm/

More articles from Materials Sciences:

nachricht Oriented hexagonal boron nitride foster new type of information carrier
25.05.2020 | Japan Advanced Institute of Science and Technology

nachricht A replaceable, more efficient filter for N95 masks
22.05.2020 | American Chemical Society

All articles from Materials Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: I-call - When microimplants communicate with each other / Innovation driver digitization - "Smart Health“

Microelectronics as a key technology enables numerous innovations in the field of intelligent medical technology. The Fraunhofer Institute for Biomedical Engineering IBMT coordinates the BMBF cooperative project "I-call" realizing the first electronic system for ultrasound-based, safe and interference-resistant data transmission between implants in the human body.

When microelectronic systems are used for medical applications, they have to meet high requirements in terms of biocompatibility, reliability, energy...

Im Focus: When predictions of theoretical chemists become reality

Thomas Heine, Professor of Theoretical Chemistry at TU Dresden, together with his team, first predicted a topological 2D polymer in 2019. Only one year later, an international team led by Italian researchers was able to synthesize these materials and experimentally prove their topological properties. For the renowned journal Nature Materials, this was the occasion to invite Thomas Heine to a News and Views article, which was published this week. Under the title "Making 2D Topological Polymers a reality" Prof. Heine describes how his theory became a reality.

Ultrathin materials are extremely interesting as building blocks for next generation nano electronic devices, as it is much easier to make circuits and other...

Im Focus: Rolling into the deep

Scientists took a leukocyte as the blueprint and developed a microrobot that has the size, shape and moving capabilities of a white blood cell. Simulating a blood vessel in a laboratory setting, they succeeded in magnetically navigating the ball-shaped microroller through this dynamic and dense environment. The drug-delivery vehicle withstood the simulated blood flow, pushing the developments in targeted drug delivery a step further: inside the body, there is no better access route to all tissues and organs than the circulatory system. A robot that could actually travel through this finely woven web would revolutionize the minimally-invasive treatment of illnesses.

A team of scientists from the Max Planck Institute for Intelligent Systems (MPI-IS) in Stuttgart invented a tiny microrobot that resembles a white blood cell...

Im Focus: NASA's Curiosity rover finds clues to chilly ancient Mars buried in rocks

By studying the chemical elements on Mars today -- including carbon and oxygen -- scientists can work backwards to piece together the history of a planet that once had the conditions necessary to support life.

Weaving this story, element by element, from roughly 140 million miles (225 million kilometers) away is a painstaking process. But scientists aren't the type...

Im Focus: Making quantum 'waves' in ultrathin materials

Study co-led by Berkeley Lab reveals how wavelike plasmons could power up a new class of sensing and photochemical technologies at the nanoscale

Wavelike, collective oscillations of electrons known as "plasmons" are very important for determining the optical and electronic properties of metals.

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

Dresden Nexus Conference 2020: Same Time, Virtual Format, Registration Opened

19.05.2020 | Event News

Aachen Machine Tool Colloquium AWK'21 will take place on June 10 and 11, 2021

07.04.2020 | Event News

International Coral Reef Symposium in Bremen Postponed by a Year

06.04.2020 | Event News

 
Latest News

Inexpensive retinal diagnostics via smartphone

25.05.2020 | Medical Engineering

Smart machine maintenance: New AI system also detects unknown faults

25.05.2020 | Information Technology

Artificial Intelligence for optimized mobile communication

25.05.2020 | Information Technology

VideoLinks
Science & Research
Overview of more VideoLinks >>>