Genotyping of Degraded and Low Copy DNA Samples
DNA typing of distinct STR loci establishes the identification of individuals or biological samples collected at crime scenes since several years. If only low amounts of DNA are available and /or the quality of the DNA is rather poor due to degradation, with commercial multiplex kits the typing often results in no or only partial DNA profiles. The invention comprises a powerful muliplex PCR system that enables simultaneous analysis of ten short amplicon STR-systems from degraded and low copy DNA samples with high sensitivity.
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