Oligonucleotide mixture for the detection of contaminations in cell cultures
Since cell culture contamination cannot be totally avoided, regular testing is a key factor for good cell culture management. The present invention provides means and methods to simultaneously detect up to 35 viral, microbial and inter-species contaminations. It facilitates sensitive and reliable determination of cell line purity. The technology is based on multiplex PCR and Luminex detection. Especially production units can profit from this cost-effective high-throughput method.
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