Application of A-Ring-Aromatized Acetyl-Minocyclines for Therapy of T-Cell Mediated Diseases
A Pentaacetylcyclin – an A-Ring aromatized and acetylated derivative of minocycline – is provided which exhibits immunomodulatory and neuroprotective action. The compound has been applied intraperitonally and orally in the mouse model of Multiple Sclerosis EAE (Experimental Autoimmune Enzephalomyelitis. Comparably low concentrations led to a relief in the acute phase of the disease.
Further Information: PDF
ESA Patentverwertungsagentur Sachsen-Anhalt GmbH
Phone: +49 (0)391/8 10 72 20
Contact
Peter Lösler
Media Contact
All latest news from the category: Technology Offerings
Newest articles
New yttrium-hydrogen compounds discovered
Researchers at the University of Bayreuth have made a significant scientific breakthrough by discovering new yttrium-hydrogen compounds having serious implications for the research on high-pressure superconductivity. High-pressure superconductivity refers to…
New AI model detects ninety percent of lymphatic cancer cases
Medical image analysis using AI has developed rapidly in recent years. Now, one of the largest studies to date has been carried out using AI-assisted image analysis of lymphoma, cancer…
UTA preps giant particle detectors for neutrino project
Excavation of caverns part of Fermilab’s Deep Underground Neutrino Experiment. With excavation work complete at the site where four gigantic particle detectors for the international Deep Underground Neutrino Experiment (DUNE) will be…