Researchers at Oxford University’s Department of Engineering Science have recently made great lengths in both engineering and monitoring 3-dimensional tissue.
Experimental hollow fibre bioreactor.
Engineering tissue involves the seeding of appropriate cells into a scaffold to form a bio-construct or matrix. The Oxford team has improved this process by developing a new kind of nutrient circulation and scaffold system for 3-D bulky tissue culture. The scaffold, made from biopolymers or synthetic polymers, has a network of capillaries embedded within it that can service the cells that attach themselves to the scaffold, allowing new tissue to grow. The capillary network is made of semi-permeable membranes whose pore size is sufficiently small to keep cells from leaving the system.
The unique Oxford system employs biodegradable porous membrane capillaries to mimic the blood capillary network in natural tissue. Traditionally, engineered tissue is governed by the diffusion of nutrients from outside the scaffold, but this system employs a system of capillaries that deliver nutrients and remove metabolic waste deep inside. Additionally, the capillary membrane is biodegradable, meaning that as time progresses the pores will widen, allowing more nutrients in and waste out. The Oxford system not only allows tissue of greater density to be grown, but as the tissue becomes bulkier, epithelial cells can be introduced in to the capillaries to promote blood vessel formation. This invention enables the culture of 3-dimensional tissues opening the possibility of growing more complex structures (such as complete organs).
Jennifer Johnson | alfa
New manufacturing process for SiC power devices opens market to more competition
14.09.2017 | North Carolina State University
Quick, Precise, but not Cold
17.05.2017 | Fraunhofer-Institut für Lasertechnik ILT
Salmonellae are dangerous pathogens that enter the body via contaminated food and can cause severe infections. But these bacteria are also known to target...
University of Maryland researchers contribute to historic detection of gravitational waves and light created by event
On August 17, 2017, at 12:41:04 UTC, scientists made the first direct observation of a merger between two neutron stars--the dense, collapsed cores that remain...
Seven new papers describe the first-ever detection of light from a gravitational wave source. The event, caused by two neutron stars colliding and merging together, was dubbed GW170817 because it sent ripples through space-time that reached Earth on 2017 August 17. Around the world, hundreds of excited astronomers mobilized quickly and were able to observe the event using numerous telescopes, providing a wealth of new data.
Previous detections of gravitational waves have all involved the merger of two black holes, a feat that won the 2017 Nobel Prize in Physics earlier this month....
Material defects in end products can quickly result in failures in many areas of industry, and have a massive impact on the safe use of their products. This is why, in the field of quality assurance, intelligent, nondestructive sensor systems play a key role. They allow testing components and parts in a rapid and cost-efficient manner without destroying the actual product or changing its surface. Experts from the Fraunhofer IZFP in Saarbrücken will be presenting two exhibits at the Blechexpo in Stuttgart from 7–10 November 2017 that allow fast, reliable, and automated characterization of materials and detection of defects (Hall 5, Booth 5306).
When quality testing uses time-consuming destructive test methods, it can result in enormous costs due to damaging or destroying the products. And given that...
Using a new cooling technique MPQ scientists succeed at observing collisions in a dense beam of cold and slow dipolar molecules.
How do chemical reactions proceed at extremely low temperatures? The answer requires the investigation of molecular samples that are cold, dense, and slow at...
23.10.2017 | Event News
17.10.2017 | Event News
10.10.2017 | Event News
24.10.2017 | Physics and Astronomy
24.10.2017 | Physics and Astronomy
24.10.2017 | Life Sciences