The new model addresses both cylindrical pores and tapering pores that simulate the á–hemolysin membrane channel. "Current models do not take into account the motion of the polymer inside the pore," says author Anatoly Kolomeisky of Rice University. "The leading monomer can move back and forth many times before it finally crosses the line to the other side of the membrane. Not accounting for this behavior introduces errors into predictions."
By improving the boundary conditions for polymer movement inside the pore, researchers demonstrated a significant increase in total time in the pore compared to earlier models. In modeling a tapering pore, they confirmed that translocation occurs faster when the polymer enters the wide side of the pore.
Possible technological applications include advances in DNA sequencing and the development of biosensors using membranes. "To design an effective sensor, it is essential to understand what you are observing and how the molecule reaches the detector," says Kolomeisky.
The article, "Polymer translocation through pores with complex geometries" by Aruna Mohan, Anatoly B. Kolomeisky, and Matteo Pasquali will be published in an upcoming issue of The Journal of Chemical Physics. See: : http://jcp.aip.org/
Journalists may request a free PDF of this article by contacting firstname.lastname@example.org
NOTE: An image is available for journalists. Please contact email@example.com
Figure Caption: "Typical Configurations of Polymer Translocation through Nanopores. Courtesy of Aruna Mohan, Rice University."ABOUT THE JOURNAL OF CHEMICAL PHYSICS
Jason Socrates Bardi | Newswise Science News
Electrocatalysis can advance green transition
23.01.2017 | Technical University of Denmark
Quantum optical sensor for the first time tested in space – with a laser system from Berlin
23.01.2017 | Ferdinand-Braun-Institut Leibniz-Institut für Höchstfrequenztechnik
For the first time ever, a cloud of ultra-cold atoms has been successfully created in space on board of a sounding rocket. The MAIUS mission demonstrates that quantum optical sensors can be operated even in harsh environments like space – a prerequi-site for finding answers to the most challenging questions of fundamental physics and an important innovation driver for everyday applications.
According to Albert Einstein's Equivalence Principle, all bodies are accelerated at the same rate by the Earth's gravity, regardless of their properties. This...
An important step towards a completely new experimental access to quantum physics has been made at University of Konstanz. The team of scientists headed by...
Yersiniae cause severe intestinal infections. Studies using Yersinia pseudotuberculosis as a model organism aim to elucidate the infection mechanisms of these...
Researchers from the University of Hamburg in Germany, in collaboration with colleagues from the University of Aarhus in Denmark, have synthesized a new superconducting material by growing a few layers of an antiferromagnetic transition-metal chalcogenide on a bismuth-based topological insulator, both being non-superconducting materials.
While superconductivity and magnetism are generally believed to be mutually exclusive, surprisingly, in this new material, superconducting correlations...
Laser-driving of semimetals allows creating novel quasiparticle states within condensed matter systems and switching between different states on ultrafast time scales
Studying properties of fundamental particles in condensed matter systems is a promising approach to quantum field theory. Quasiparticles offer the opportunity...
19.01.2017 | Event News
10.01.2017 | Event News
09.01.2017 | Event News
23.01.2017 | Health and Medicine
23.01.2017 | Physics and Astronomy
23.01.2017 | Process Engineering