Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

World first: lungs awaiting transplant preserved 11 hours outside body

15.10.2013
The multidisciplinary transplant team at University Hospitals Leuven successfully preserved a set of donor lungs for over eleven hours with the help of a machine, the longest period ever reported.

The OCS LUNG™ machine continually flushes and oxygenates donor lungs at room temperature.

The lengthy preservation time was necessary because the patient needed a liver transplant immediately prior to the lung transplant. The patient has since left the hospital and is in good health.

The patient, who suffered from chronic lung failure, developed sudden acute liver problems and went into a coma. The only surgical option for a patient with a terminal lung disease and a terminal liver disease is a combined lung and liver transplant.

But such double transplants pose a serious timing problem, says Dr. Dirk Van Raemdonck, who helped perform the surgery: "Normally, the lung transplant is carried out before the liver transplant. A donor lung typically can only be preserved outside the body for a maximum of ten hours. And a lung transplant can only be successful if the liver is still working properly. That is why we needed to transplant the liver before the lungs for this patient. To keep the donor lungs in good shape long enough after removal from the donor and prior to transplantation, our medical team used a new preservation technique."

The lungs were not put on ice as they usually are, but were preserved using a machine (OCS LUNG™) that provided continual flushing and oxygen at room temperature. Dr. Van Raemdonck: "The machine enabled us to keep the lungs outside the body for more than eleven hours with no negative effects, the longest period ever reported – a world first."

World first

The new technique enables doctors to preserve lungs outside the body longer. The machine also provides an analysis of lung quality and can even improve lung function in anticipation of the transplant. A similar machine already exists for kidneys and results show that older kidneys preserved using that machine functioned better immediately after transplantation than kidneys preserved on ice did.

Currently, however, the new technique is not being reimbursed by insurance providers. The technique is being used only in special cases. Costs for this transplantation were covered entirely by University Hospitals Leuven and the maker of the machine.

The combined lung and liver transplant was performed last July by University Hospitals Leuven's multidisciplinary transplant team, which includes specialists in hepatology (led by Dr. Frederik Nevens), abdominal transplant surgery (led by Dr. Jacques Pirenne), pneumology (led by Dr. Geert Verleden) and thoracic surgery (led by Dr. Paul De Leyn).

University Hospitals Leuven is an independent network of research hospitals affiliated with KU Leuven (University of Leuven) in Leuven, Belgium.

http://www.kuleuven.be/english/news/world-first-lungs-awaiting-transplant-preserved-11-hours-outside-body

Contact

Dr. Dirk Van Raemdonck, tel. +32 16 34 09 09, (mobile) +32 484 44 34 18, email dirk.vanraemdonck@uzleuven.be

The photo in attachment shows the pair of donor lungs being preserved by the OCS LUNG™ machine (Transmedics, Andover, MA, USA).

Follow us on Twitter (www.twitter.com/uzleuven and www.twitter.com/LeuvenU) for the latest news from University Hospitals Leuven and KU Leuven.

Jack McMartin | alfa
Further information:
http://www.kuleuven.be

More articles from Health and Medicine:

nachricht UT Southwestern scientists discover new clues to how weight loss is regulated
24.10.2014 | UT Southwestern Medical Center

nachricht Bipolar Disorder Discovery at the Nano Level
23.10.2014 | Northwestern University

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Anzeige

Anzeige

Event News

Comparing Apples and Oranges? A Colloquium on International Comparative Urban Research

22.10.2014 | Event News

Battery Conference April 2015 in Aachen

16.10.2014 | Event News

Experts discuss new developments in the field of stem cell research and cell therapy

10.10.2014 | Event News

 
Latest News

Precise and programmable biological circuits

24.10.2014 | Life Sciences

Desert Streams: Deceptively Simple

24.10.2014 | Earth Sciences

Modernized stainless steel continuous caster from Siemens goes on stream at Posco

24.10.2014 | Press release

VideoLinks
B2B-VideoLinks
More VideoLinks >>>