Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Thermography confirms improvement of wound healing by water-filtered infrared-A (wIRA)

22.10.2008
Water-filtered infrared-A (wIRA) as a special form of heat radiation can enable and improve wound healing in non-healing chronic venous stasis ulcers. wIRA can considerably alleviate the pain and diminish an elevated wound exudation and inflammation. wIRA increases temperature, oxygen partial pressure, and perfusion in the tissue.

In an original paper, just published in the interdisciplinary medical e-Journal "GMS German Medical Science" of the Association of the Scientific Medical Societies in Germany (AWMF), the beneficial effects of wIRA in chronic venous stasis ulcers could be demonstrated by clinical assessments and as well by extensive thermographic investigations.

It is estimated that at least 1% of the population in industrialised countries will suffer from leg ulcer at some time. A prospective study of the University Tromsø/Norway and the Hospital in Hillerød/Denmark of 10 patients with non-healing chronic venous stasis ulcers of the lower legs, in which other therapies were not successful, resulted under therapy with wIRA in a complete or almost complete wound healing (96-100% reduction of wound area) in 7 of 10 patients and a reduction of the ulcer size in another 2 of 10 patients. The uncovered wounds of the patients were irradiated two to five times per week for 30 minutes. Treatment continued for a period of up to 2 months (typically until closure or nearly closure of the ulcer was achieved).

An example of a successful course of therapy with wIRA irradiation is demonstrated in Figure 1 with normal view, thermographic image and temperature profile across the ulcer, in each case before therapy and after completion of therapy.

Among the 6 patients without concomitant problems (peripheral occlusive arterial disease, smoking or lacking compression garment therapy) a complete or almost complete wound healing was achieved without any exception. Even in the 4 patients with concomitant problems clear reductions of wound area were reached in 4 of the 5 ulcers including one complete wound closure. In one patient a randomized controlled side comparison was possible (therapy of one leg with an ulcer with wIRA and visible light, therapy of the other leg with another ulcer with a control group radiator, emitting only visible light without wIRA) and revealed marked differences in favour of wIRA.

In addition the study showed under therapy with wIRA a clear reduction of pain and required pain medication (e.g. from 15 to 0 pain tablets per day) and a normalization of the thermographic image. Prior to the start of therapy typically the rim of the ulcer was hyperthermic, accompanied with a relative hypothermic ulcer base, partly associated with up to 4.5°C temperature gradiance. At the end of the course of therapy the temperature differences were mostly balanced. All assessments using visual analogue scales (VAS: pain sensation of the patient in the wound area, overall rating of the effect of the irradiation by the patient and by the clinical investigator, overall assessment of the feeling of the patient of the wound area, overall evaluation of the wound healing process by the clinical investigator, overall assessment of the cosmetic appearance by the patient and by the clinical investigator) improved remarkably during the period of irradiation therapy and commensurated with the improvement of the quality of life.

Wound healing and infection defence depend decisively on a sufficient supply with energy and oxygen. The central portion of chronic wounds is often clearly hypoxic and relatively hypothermic - as thermographically shown in the study -, representing a deficient energy supply of the tissue, which impedes wound healing or even makes it impossible. wIRA produces a therapeutically usable field of heat in the tissue and increases tissue temperature, tissue oxygen partial pressure, and tissue perfusion. These three factors are vital for a sufficient tissue supply with energy and oxygen. The good clinical effect of wIRA on wounds and wound infections can be explained by the improvement of both the energy supply per time (increase of metabolic rate) and the oxygen supply. In addition wIRA has non-thermal and non-thermic effects, which are based on putting direct stimuli on cells and cellular structures.

Publication:

Mercer JB, Nielsen SP, Hoffmann G. Improvement of wound healing by water-filtered infrared-A (wIRA) in patients with chronic venous stasis ulcers of the lower legs including evaluation using infrared thermography. GMS Ger Med Sci. 2008;6:Doc11.
Online available from: http://www.egms.de/pdf/gms/2008-6/000056.pdf (PDF) and http://www.egms.de/en/gms/2008-6/000056.shtml (HTML).

The freely available publication includes 10 patient appendices and 2 video sequences.

Wolfgang Müller | idw
Further information:
http://awmf.org
http://www.egms.de/en/gms/2008-6/000056.shtml
http://www.egms.de/pdf/gms/2008-6/000056.pdf

More articles from Health and Medicine:

nachricht 3D images of cancer cells in the body: Medical physicists from Halle present new method
16.05.2018 | Martin-Luther-Universität Halle-Wittenberg

nachricht Better equipped in the fight against lung cancer
16.05.2018 | Friedrich-Alexander-Universität Erlangen-Nürnberg

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: LZH showcases laser material processing of tomorrow at the LASYS 2018

At the LASYS 2018, from June 5th to 7th, the Laser Zentrum Hannover e.V. (LZH) will be showcasing processes for the laser material processing of tomorrow in hall 4 at stand 4E75. With blown bomb shells the LZH will present first results of a research project on civil security.

At this year's LASYS, the LZH will exhibit light-based processes such as cutting, welding, ablation and structuring as well as additive manufacturing for...

Im Focus: Self-illuminating pixels for a new display generation

There are videos on the internet that can make one marvel at technology. For example, a smartphone is casually bent around the arm or a thin-film display is rolled in all directions and with almost every diameter. From the user's point of view, this looks fantastic. From a professional point of view, however, the question arises: Is that already possible?

At Display Week 2018, scientists from the Fraunhofer Institute for Applied Polymer Research IAP will be demonstrating today’s technological possibilities and...

Im Focus: Explanation for puzzling quantum oscillations has been found

So-called quantum many-body scars allow quantum systems to stay out of equilibrium much longer, explaining experiment | Study published in Nature Physics

Recently, researchers from Harvard and MIT succeeded in trapping a record 53 atoms and individually controlling their quantum state, realizing what is called a...

Im Focus: Dozens of binaries from Milky Way's globular clusters could be detectable by LISA

Next-generation gravitational wave detector in space will complement LIGO on Earth

The historic first detection of gravitational waves from colliding black holes far outside our galaxy opened a new window to understanding the universe. A...

Im Focus: Entangled atoms shine in unison

A team led by Austrian experimental physicist Rainer Blatt has succeeded in characterizing the quantum entanglement of two spatially separated atoms by observing their light emission. This fundamental demonstration could lead to the development of highly sensitive optical gradiometers for the precise measurement of the gravitational field or the earth's magnetic field.

The age of quantum technology has long been heralded. Decades of research into the quantum world have led to the development of methods that make it possible...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

Save the date: Forum European Neuroscience – 07-11 July 2018 in Berlin, Germany

02.05.2018 | Event News

Invitation to the upcoming "Current Topics in Bioinformatics: Big Data in Genomics and Medicine"

13.04.2018 | Event News

Unique scope of UV LED technologies and applications presented in Berlin: ICULTA-2018

12.04.2018 | Event News

 
Latest News

Research reveals how order first appears in liquid crystals

23.05.2018 | Life Sciences

Space-like gravity weakens biochemical signals in muscle formation

23.05.2018 | Life Sciences

NIST puts the optical microscope under the microscope to achieve atomic accuracy

23.05.2018 | Physics and Astronomy

VideoLinks
Science & Research
Overview of more VideoLinks >>>