Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Singapore's IBN and NUH to test cutting-edge materials to treat eye diseases

05.11.2009
World's first photochromic contact lens that darken with sunlight exposure among Institute of Bioengineering and Nanotechnology advances

Marking a significant bench to bedside research milestone in Singapore, the Institute of Bioengineering and Nanotechnology (IBN), the world's first bioengineering and nanotechnology research institute, and the National University Hospital (NUH) launched the IBN iCare and the NUH Eye Centre @ Biopolis at an official opening ceremony officiated by the Senior Minister of State for Trade and Industry and Education, S. Iswaran, at the Biopolis on Nov. 3, 2009.

Collaborations between researchers and clinicians are critical to speed up the translation of basic scientific discoveries into clinical applications, and develop new medical products and treatments. IBN iCare is the first research laboratory in Singapore to focus on the development of cutting-edge nanomaterials for ocular therapy.

The NUH Eye Centre @ Biopolis will provide a clinical research environment that facilitates the development of new materials and techniques for ophthalmology practice. IBN's nanostructured ocular materials will undergo clinical trials at the NUH Eye Centre prior to commercial applications.

Since 2003, IBN has been revolutionizing medical treatment with sophisticated biomaterials and systems for delivering therapeutics to diseased cells and organs. This key research thrust at IBN has led to the synthesis of a novel drug-loaded contact lens that can deliver medication more effectively than eye drops for the treatment of eye diseases such as glaucoma. The latest ocular research invention created by IBN is the world's first photochromic contact lens that will darken upon exposure to sunlight to protect the eyes against harmful ultraviolet radiation and glare. The lenses will conveniently adapt to changes in light and provide optimal indoor and outdoor vision.

"IBN's mission is to conduct strategic research that addresses important biomedical problems through novel technology platforms that present major commercial potential. The launch of IBN iCare and our collaboration with NUH symbolize our commitment towards establishing Singapore as an international, world class biomedical hub. By bridging the gap from bench to bedside, we are well positioned to facilitate the commercialization of our research innovations," said Professor Jackie Y. Ying, IBN Founding Executive Director.

Recognizing the commercial potential of IBN's ocular biomaterials, Exploit Technologies Pte Ltd (ETPL), the strategic marketing and commercialization arm of the Agency for Science, Technology and Research (A*STAR), provided a S$5 million Flagship Fund to set up IBN iCare. IBN iCare will accelerate the translation of strategic research in vision care to viable medical products and treatments. Its mission is to incubate start-up companies in vision care, and attract more global partners to Singapore to create a major commercial impact on myopia and vision impairment treatment.

Boon Swan Foo, Executive Chairman of Exploit Technologies, said, "Exploit Technologies is pleased to have partnered IBN and NUH in building this tripartite commercialisation effort. The bringing together of clinicians with scientists and commercial people to this juncture is due to the unrelenting effort of the key players, including Dr. Muhammad Tani, Professor Jackie Ying and Associate Professor Paul Chew who have worked hard to overcome obstacles along the way. Our team started to work on the project since 2005; it was a time when the market was not ready for adoption of the drug eluting nanoporous contact lens technology. We ploughed the market, evolved our marketing strategies, and essentially created a market when there was none. Through our efforts, the technology was licensed to a MNC in 2006, with a contract value of more than S$100 million. To further exploit the technology's commercial potential, we held discussions with clinicians and industry players to find out other potential applications; and the idea of the NUH Eye Centre was born in 2007. To ensure the success of this meaningful project, Exploit Technologies launched a Flagship project, coupled with an S$5 million funding, to help set up IBN iCare and NUH Eye Centre @ Biopolis.

"Today, we see the fruits of our labour. I am delighted that big players like SAF and Carl Zeiss are partnering us in the effort to take R&D from the lab to market. Additionally, two Singapore-based companies have already expressed interest to license IBN's photochromic contact lens. I am encouraged that diverse teams with proper leadership and good technologies can lead to a successful start of a great future ahead."

In addition to research, the NUH Eye Centre @ Biopolis will also provide a wide range of eye care services, LASIK and refractive surgery for patients. The patient-centric centre is designed with the patient's interest and safety in mind. For example, to improve the patient's experience, the configuration of the centre optimises the patient flow by guiding them through the various eye-check stations. The LASIK operating suite also complies with stringent guidelines to enhance patients' safety. Another interesting feature is the see-through glass that allows the patients' family members to observe the LASIK procedure. Innovative treatment of vision correction using IBN's biomaterials will also be widely offered through the NUH Eye Centre @ Biopolis.

Joe Sim, NUH Chief Executive Officer, said, "Having one of our eye facilities located in the Biopolis means we are right within the research hub. This will facilitate greater opportunities for research collaboration which is aligned with our focus as an academic medical centre. Our partnership with IBN will allow us to work closely with researchers on projects that will potentially translate to better care to benefit our patients and Singaporeans."

The close proximity of the eye clinic to IBN iCare at the Biopolis will strengthen the partnership between NUHS ophthalmologists and IBN researchers to better meet the healthcare needs of the patients. Besides eye care, IBN scientists can also work closely with clinicians at NUH to advance collaborations in IBN's four research areas: Drug and Gene Delivery, Cell and Tissue Engineering, Biosensors and Biodevices, Pharmaceuticals Synthesis and Nanobiotechnology.

The initiative by IBN iCare and NUH Eye Centre @ Biopolis will also expedite the route to commercialization by bridging the gap from bench to industry. IBN is working with Carl Zeiss, a global leader in the optical industries, on the development of technologies and treatments associated with IBN's innovative ocular biomaterials. The Singapore Armed Forces (SAF) Medical Corps is also partnering with IBN and NUH in research and training for vision correction technology to address the problems of myopia and ocular trauma in SAF operations.

Elena Tan | EurekAlert!
Further information:
http://www.ibn.a-star.edu.sg
http://www.a-star.edu.sg

Further reports about: Bioengineering Biopolis Eye Tracking Flagship IBN LASIK NUH Nanotechnology Singapore Tissue Engineering

More articles from Health and Medicine:

nachricht Observing the cell's protein factories during self-assembly
15.06.2018 | Charité - Universitätsmedizin Berlin

nachricht Scientists unravel molecular mechanisms of Parkinson's disease
13.06.2018 | The Francis Crick Institute

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: AchemAsia 2019 will take place in Shanghai

Moving into its fourth decade, AchemAsia is setting out for new horizons: The International Expo and Innovation Forum for Sustainable Chemical Production will take place from 21-23 May 2019 in Shanghai, China. With an updated event profile, the eleventh edition focusses on topics that are especially relevant for the Chinese process industry, putting a strong emphasis on sustainability and innovation.

Founded in 1989 as a spin-off of ACHEMA to cater to the needs of China’s then developing industry, AchemAsia has since grown into a platform where the latest...

Im Focus: First real-time test of Li-Fi utilization for the industrial Internet of Things

The BMBF-funded OWICELLS project was successfully completed with a final presentation at the BMW plant in Munich. The presentation demonstrated a Li-Fi communication with a mobile robot, while the robot carried out usual production processes (welding, moving and testing parts) in a 5x5m² production cell. The robust, optical wireless transmission is based on spatial diversity; in other words, data is sent and received simultaneously by several LEDs and several photodiodes. The system can transmit data at more than 100 Mbit/s and five milliseconds latency.

Modern production technologies in the automobile industry must become more flexible in order to fulfil individual customer requirements.

Im Focus: Sharp images with flexible fibers

An international team of scientists has discovered a new way to transfer image information through multimodal fibers with almost no distortion - even if the fiber is bent. The results of the study, to which scientist from the Leibniz-Institute of Photonic Technology Jena (Leibniz IPHT) contributed, were published on 6thJune in the highly-cited journal Physical Review Letters.

Endoscopes allow doctors to see into a patient’s body like through a keyhole. Typically, the images are transmitted via a bundle of several hundreds of optical...

Im Focus: Photoexcited graphene puzzle solved

A boost for graphene-based light detectors

Light detection and control lies at the heart of many modern device applications, such as smartphone cameras. Using graphene as a light-sensitive material for...

Im Focus: Water is not the same as water

Water molecules exist in two different forms with almost identical physical properties. For the first time, researchers have succeeded in separating the two forms to show that they can exhibit different chemical reactivities. These results were reported by researchers from the University of Basel and their colleagues in Hamburg in the scientific journal Nature Communications.

From a chemical perspective, water is a molecule in which a single oxygen atom is linked to two hydrogen atoms. It is less well known that water exists in two...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

Munich conference on asteroid detection, tracking and defense

13.06.2018 | Event News

2nd International Baltic Earth Conference in Denmark: “The Baltic Sea region in Transition”

08.06.2018 | Event News

ISEKI_Food 2018: Conference with Holistic View of Food Production

05.06.2018 | Event News

 
Latest News

New ID pictures of conducting polymers discover a surprise ABBA fan

18.06.2018 | Life Sciences

The car of the future – sleeper cars and travelling offices too?

18.06.2018 | Automotive Engineering

Scientists predict a new superhard material with unique properties

18.06.2018 | Materials Sciences

VideoLinks
Science & Research
Overview of more VideoLinks >>>