Researchers from Imperial College London, who are evaluating multiple candidate vaccines designed to prevent HIV, argue that Western governments and funding agencies must commit to sharing technology and expertise with those in the developing world on a long-term basis.
The researchers have been working with local scientists in Uganda and other sites in the developing world to enable large-scale international trials of potential vaccines against HIV. They argue their work shows that it is both feasible and desirable to carry out high-quality trials in developing countries, but that more state-of-the-art laboratories are needed in the developing world to support such trials and enable the roll-out of antiretroviral drugs.
The authors write that people in countries like Uganda wish to take ownership of, or at the very least be equal partners in, efforts to develop treatments for HIV to benefit their population.
“Old fashioned ‘parachute science’ – where scientists from the developed world flew in, bled a few patients, and immediately returned to their country of origin with their samples, are no longer required or acceptable. In-house development and research is an effective and efficient way forward,” said Professor Frances Gotch, one of the commentary’s authors from the Division of Investigative Science at Imperial College.
Uganda is a relative success story in relation to other parts of sub-Saharan Africa in terms of how it has dealt with the spread of HIV, thanks to a National AIDS Control programme, which was established early in the epidemic. Nonetheless, one million people in the country are living with HIV and contributions from the West have been and continue to be crucial in Uganda and elsewhere, say the authors.
Collaborations across sub-Saharan Africa have so far enabled the creation of network of state-of-the-art laboratories, staffed by local scientists and technologists. Cooperation between the Ugandan government and international bodies has enabled the development of research which has led to improved HIV screening and counselling; free mosquito nets and water purification to prevent opportunistic infections; and free testing and treatment for basic infections of danger to those living with AIDS.
“Western governments and funding agencies need to continue to build capacity and train future generations of scientists and doctors on-site in new technologies,” added Professor Gotch. “Countries need resources to maintain and sustain not only the facilities and equipment, but also staff in these countries who are trained and motivated. It is most important to give countries the capacity to train the trainers in their country so that knowledge can be shared and developed there.”
The commentary is part of the Council of Science Editors' global theme issue on poverty and human development, launched today by the National Institutes of Health to coincide with the publication of related research by more than 230 journals worldwide.
Laura Gallagher | alfa
GLUT5 fluorescent probe fingerprints cancer cells
20.04.2018 | Michigan Technological University
Scientists re-create brain neurons to study obesity and personalize treatment
20.04.2018 | Cedars-Sinai Medical Center
University of Connecticut researchers have created a biodegradable composite made of silk fibers that can be used to repair broken load-bearing bones without the complications sometimes presented by other materials.
Repairing major load-bearing bones such as those in the leg can be a long and uncomfortable process.
Study published in the journal ACS Applied Materials & Interfaces is the outcome of an international effort that included teams from Dresden and Berlin in Germany, and the US.
Scientists at the Helmholtz-Zentrum Dresden-Rossendorf (HZDR) together with colleagues from the Helmholtz-Zentrum Berlin (HZB) and the University of Virginia...
Novel highly efficient and brilliant gamma-ray source: Based on model calculations, physicists of the Max PIanck Institute for Nuclear Physics in Heidelberg propose a novel method for an efficient high-brilliance gamma-ray source. A giant collimated gamma-ray pulse is generated from the interaction of a dense ultra-relativistic electron beam with a thin solid conductor. Energetic gamma-rays are copiously produced as the electron beam splits into filaments while propagating across the conductor. The resulting gamma-ray energy and flux enable novel experiments in nuclear and fundamental physics.
The typical wavelength of light interacting with an object of the microcosm scales with the size of this object. For atoms, this ranges from visible light to...
Stable joint cartilage can be produced from adult stem cells originating from bone marrow. This is made possible by inducing specific molecular processes occurring during embryonic cartilage formation, as researchers from the University and University Hospital of Basel report in the scientific journal PNAS.
Certain mesenchymal stem/stromal cells from the bone marrow of adults are considered extremely promising for skeletal tissue regeneration. These adult stem...
In the fight against cancer, scientists are developing new drugs to hit tumor cells at so far unused weak points. Such a “sore spot” is the protein complex...
13.04.2018 | Event News
12.04.2018 | Event News
09.04.2018 | Event News
20.04.2018 | Physics and Astronomy
20.04.2018 | Interdisciplinary Research
20.04.2018 | Physics and Astronomy