For the study, the researchers designed a human colon model with 17 lesions to simulate polyps and six lesions to simulate fecal matter. Two abdominal radiologists independently reviewed the MDCT scans of the model. The researchers found that accuracy for detection of the polyps was 73% and 69% at the routinely used settings of 120 and 140 kVp, and 87% and 82% at the lower 80 kVp.
"CT colonography can be a valuable non-invasive tool for screening for polyps and pre-cancerous lesions; however, every patient has to undergo a tedious and uncomfortable colonic preparation prior to the procedure. The recent introduction of dual-energy CT scanners provides a window of opportunity to explore the role of dual-energy CT to differentiate between polyps and fecal matter in an unprepped colon. Our study is the first step in this direction," said Sunit Sebastian, MD, of Emory University School of Medicine and lead author of the study.
The next step for the researchers is to test whether lower CT settings would work with actual patients. "We have since obtained an IRB approval to perform a dual-energy CT colonography in patients. If favorable results are obtained in the patient population, it would mean that we could avoid or totally bypass the uncomfortable colonic preparation, thereby making CT colonography more patient-friendly. This would further enhance patient compliance for screening for colon cancer," said Dr. Sebastian.
Necoya Lightsey | EurekAlert!
Study suggests possible new target for treating and preventing Alzheimer's
02.12.2016 | Oregon Health & Science University
The first analysis of Ewing's sarcoma methyloma opens doors to new treatments
01.12.2016 | IDIBELL-Bellvitge Biomedical Research Institute
A multi-institutional research collaboration has created a novel approach for fabricating three-dimensional micro-optics through the shape-defined formation of porous silicon (PSi), with broad impacts in integrated optoelectronics, imaging, and photovoltaics.
Working with colleagues at Stanford and The Dow Chemical Company, researchers at the University of Illinois at Urbana-Champaign fabricated 3-D birefringent...
In experiments with magnetic atoms conducted at extremely low temperatures, scientists have demonstrated a unique phase of matter: The atoms form a new type of quantum liquid or quantum droplet state. These so called quantum droplets may preserve their form in absence of external confinement because of quantum effects. The joint team of experimental physicists from Innsbruck and theoretical physicists from Hannover report on their findings in the journal Physical Review X.
“Our Quantum droplets are in the gas phase but they still drop like a rock,” explains experimental physicist Francesca Ferlaino when talking about the...
The Max Planck Institute for Physics (MPP) is opening up a new research field. A workshop from November 21 - 22, 2016 will mark the start of activities for an innovative axion experiment. Axions are still only purely hypothetical particles. Their detection could solve two fundamental problems in particle physics: What dark matter consists of and why it has not yet been possible to directly observe a CP violation for the strong interaction.
The “MADMAX” project is the MPP’s commitment to axion research. Axions are so far only a theoretical prediction and are difficult to detect: on the one hand,...
Broadband rotational spectroscopy unravels structural reshaping of isolated molecules in the gas phase to accommodate water
In two recent publications in the Journal of Chemical Physics and in the Journal of Physical Chemistry Letters, researchers around Melanie Schnell from the Max...
The efficiency of power electronic systems is not solely dependent on electrical efficiency but also on weight, for example, in mobile systems. When the weight of relevant components and devices in airplanes, for instance, is reduced, fuel savings can be achieved and correspondingly greenhouse gas emissions decreased. New materials and components based on gallium nitride (GaN) can help to reduce weight and increase the efficiency. With these new materials, power electronic switches can be operated at higher switching frequency, resulting in higher power density and lower material costs.
Researchers at the Fraunhofer Institute for Solar Energy Systems ISE together with partners have investigated how these materials can be used to make power...
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