For the study, the researchers designed a human colon model with 17 lesions to simulate polyps and six lesions to simulate fecal matter. Two abdominal radiologists independently reviewed the MDCT scans of the model. The researchers found that accuracy for detection of the polyps was 73% and 69% at the routinely used settings of 120 and 140 kVp, and 87% and 82% at the lower 80 kVp.
"CT colonography can be a valuable non-invasive tool for screening for polyps and pre-cancerous lesions; however, every patient has to undergo a tedious and uncomfortable colonic preparation prior to the procedure. The recent introduction of dual-energy CT scanners provides a window of opportunity to explore the role of dual-energy CT to differentiate between polyps and fecal matter in an unprepped colon. Our study is the first step in this direction," said Sunit Sebastian, MD, of Emory University School of Medicine and lead author of the study.
The next step for the researchers is to test whether lower CT settings would work with actual patients. "We have since obtained an IRB approval to perform a dual-energy CT colonography in patients. If favorable results are obtained in the patient population, it would mean that we could avoid or totally bypass the uncomfortable colonic preparation, thereby making CT colonography more patient-friendly. This would further enhance patient compliance for screening for colon cancer," said Dr. Sebastian.
Necoya Lightsey | EurekAlert!
NIH scientists describe potential antibody treatment for multidrug-resistant K. pneumoniae
14.03.2018 | NIH/National Institute of Allergy and Infectious Diseases
Researchers identify key step in viral replication
13.03.2018 | University of Pittsburgh Schools of the Health Sciences
Animal photoreceptors capture light with photopigments. Researchers from the University of Göttingen have now discovered that these photopigments fulfill an...
On 15 March, the AWI research aeroplane Polar 5 will depart for Greenland. Concentrating on the furthest northeast region of the island, an international team...
The world’s second-largest ice shelf was the destination for a Polarstern expedition that ended in Punta Arenas, Chile on 14th March 2018. Oceanographers from...
At the 2018 ILA Berlin Air Show from April 25–29, the Fraunhofer Institute for Laser Technology ILT is showcasing extreme high-speed Laser Material Deposition (EHLA): A video documents how for metal components that are highly loaded, EHLA has already proved itself as an alternative to hard chrome plating, which is now allowed only under special conditions.
When the EU restricted the use of hexavalent chromium compounds to special applications requiring authorization, the move prompted a rethink in the surface...
At the ILA Berlin, hall 4, booth 202, Fraunhofer FHR will present two radar sensors for navigation support of drones. The sensors are valuable components in the implementation of autonomous flying drones: they function as obstacle detectors to prevent collisions. Radar sensors also operate reliably in restricted visibility, e.g. in foggy or dusty conditions. Due to their ability to measure distances with high precision, the radar sensors can also be used as altimeters when other sources of information such as barometers or GPS are not available or cannot operate optimally.
Drones play an increasingly important role in the area of logistics and services. Well-known logistic companies place great hope in these compact, aerial...
16.03.2018 | Event News
13.03.2018 | Event News
08.03.2018 | Event News
16.03.2018 | Earth Sciences
16.03.2018 | Physics and Astronomy
16.03.2018 | Life Sciences