"By combining conventional techniques with more modern techniques, we were able to better diagnose and determine the best options for patients with oral cancer," said J.B. Epstein, lead author of the study and Professor at the University of Illinois at Chicago. "This approach to diagnosing oral cancer may lead to easier identification of serious pathology, significantly lessening the need for unnecessary biopsies without additional risk of false negatives."
Patients with early stage oral cancer are typically examined by their doctor for suspicious areas in the mouth and throat area. Doctors in this study wanted to test the value of two diagnostic aids in evaluating lesions in the oral cavity. Chemiluminescent light, or brand name Vizilite and toluidine blue, a pharmaceutical grade dye, were used in addition to the conventional, visual and manual observations of the patient.
Patients were given routine visual examinations under incandescent light for suspicious lesions. The lesions that were deemed suspicious were then assessed with Vizilite, followed by the toluidine blue dye and then biopsied. Doctors then compared the findings from the conventional exam to the advanced, illumination and stain exam.
This study found that of the 84 patients studied, Vizilite improved either the brightness or sharpness of the identified lesions by 61 percent. Only biopsing lesions which retained the toluidine blue stain reduced the false positive rate by nearly 59 percent while maintaining zero false negatives.
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20.01.2017 | University of Illinois at Urbana-Champaign
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19.01.2017 | Rheinische Friedrich-Wilhelms-Universität Bonn
An important step towards a completely new experimental access to quantum physics has been made at University of Konstanz. The team of scientists headed by...
Yersiniae cause severe intestinal infections. Studies using Yersinia pseudotuberculosis as a model organism aim to elucidate the infection mechanisms of these...
Researchers from the University of Hamburg in Germany, in collaboration with colleagues from the University of Aarhus in Denmark, have synthesized a new superconducting material by growing a few layers of an antiferromagnetic transition-metal chalcogenide on a bismuth-based topological insulator, both being non-superconducting materials.
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Laser-driving of semimetals allows creating novel quasiparticle states within condensed matter systems and switching between different states on ultrafast time scales
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Among the general public, solar thermal energy is currently associated with dark blue, rectangular collectors on building roofs. Technologies are needed for aesthetically high quality architecture which offer the architect more room for manoeuvre when it comes to low- and plus-energy buildings. With the “ArKol” project, researchers at Fraunhofer ISE together with partners are currently developing two façade collectors for solar thermal energy generation, which permit a high degree of design flexibility: a strip collector for opaque façade sections and a solar thermal blind for transparent sections. The current state of the two developments will be presented at the BAU 2017 trade fair.
As part of the “ArKol – development of architecturally highly integrated façade collectors with heat pipes” project, Fraunhofer ISE together with its partners...
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