"By combining conventional techniques with more modern techniques, we were able to better diagnose and determine the best options for patients with oral cancer," said J.B. Epstein, lead author of the study and Professor at the University of Illinois at Chicago. "This approach to diagnosing oral cancer may lead to easier identification of serious pathology, significantly lessening the need for unnecessary biopsies without additional risk of false negatives."
Patients with early stage oral cancer are typically examined by their doctor for suspicious areas in the mouth and throat area. Doctors in this study wanted to test the value of two diagnostic aids in evaluating lesions in the oral cavity. Chemiluminescent light, or brand name Vizilite and toluidine blue, a pharmaceutical grade dye, were used in addition to the conventional, visual and manual observations of the patient.
Patients were given routine visual examinations under incandescent light for suspicious lesions. The lesions that were deemed suspicious were then assessed with Vizilite, followed by the toluidine blue dye and then biopsied. Doctors then compared the findings from the conventional exam to the advanced, illumination and stain exam.
This study found that of the 84 patients studied, Vizilite improved either the brightness or sharpness of the identified lesions by 61 percent. Only biopsing lesions which retained the toluidine blue stain reduced the false positive rate by nearly 59 percent while maintaining zero false negatives.
New malaria analysis method reveals disease severity in minutes
14.08.2017 | University of British Columbia
New type of blood cells work as indicators of autoimmunity
14.08.2017 | Instituto de Medicina Molecular
Whether you call it effervescent, fizzy, or sparkling, carbonated water is making a comeback as a beverage. Aside from quenching thirst, researchers at the University of Illinois at Urbana-Champaign have discovered a new use for these "bubbly" concoctions that will have major impact on the manufacturer of the world's thinnest, flattest, and one most useful materials -- graphene.
As graphene's popularity grows as an advanced "wonder" material, the speed and quality at which it can be manufactured will be paramount. With that in mind,...
Physicists at the University of Bonn have managed to create optical hollows and more complex patterns into which the light of a Bose-Einstein condensate flows. The creation of such highly low-loss structures for light is a prerequisite for complex light circuits, such as for quantum information processing for a new generation of computers. The researchers are now presenting their results in the journal Nature Photonics.
Light particles (photons) occur as tiny, indivisible portions. Many thousands of these light portions can be merged to form a single super-photon if they are...
For the first time, scientists have shown that circular RNA is linked to brain function. When a RNA molecule called Cdr1as was deleted from the genome of mice, the animals had problems filtering out unnecessary information – like patients suffering from neuropsychiatric disorders.
While hundreds of circular RNAs (circRNAs) are abundant in mammalian brains, one big question has remained unanswered: What are they actually good for? In the...
An experimental small satellite has successfully collected and delivered data on a key measurement for predicting changes in Earth's climate.
The Radiometer Assessment using Vertically Aligned Nanotubes (RAVAN) CubeSat was launched into low-Earth orbit on Nov. 11, 2016, in order to test new...
A study led by scientists of the Max Planck Institute for the Structure and Dynamics of Matter (MPSD) at the Center for Free-Electron Laser Science in Hamburg presents evidence of the coexistence of superconductivity and “charge-density-waves” in compounds of the poorly-studied family of bismuthates. This observation opens up new perspectives for a deeper understanding of the phenomenon of high-temperature superconductivity, a topic which is at the core of condensed matter research since more than 30 years. The paper by Nicoletti et al has been published in the PNAS.
Since the beginning of the 20th century, superconductivity had been observed in some metals at temperatures only a few degrees above the absolute zero (minus...
16.08.2017 | Event News
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17.08.2017 | Physics and Astronomy
17.08.2017 | Earth Sciences
17.08.2017 | Physics and Astronomy