An organic compound that creates a realistic beachy glow while inducing a natural sun block effect in your skin may be just around the corner, as scientists at the University of Kentucky are testing a treatment that enhances melanin production in animal models.
"We are in the process of evaluating forskolin, a derivative of the plant Pletranthus barbatus, for safety when applied to the skin. We know it stimulates melanin, but we need to know that it does so without adverse effect. So far, results are promising," said Dr. John D'Orazio of the UK Department of Pediatrics,the Markey Cancer Center and the Graduate Center for Toxicology.
Many people use sunless tanning products to achieve a tan look without risking the UV damage that causes skin cancer and wrinkles. However, sunless tanners currently on the market use a chemical that dyes skin a brown or orange shade. With no sun protection, skin remains vulnerable to burns and damage. Some people become frustrated with the tricky application of sunless tanners (as anyone who has ever left the house with orange knees and elbows can attest) and either give up entirely, or turn to the sun and tanning beds. Getting a tan either by sitting out in the sun or in a tanning bed currently comes with the bad side effects of ultraviolet radiation, namely sun spots, skin thickening and skin cancer. This new approach uses a lotion that fools the skin into thinking it has been out in the sun (causing natural tanning to happen) without the bad side effects of UV light.
Even those who do not desire a tanned look and use copious amounts of sun block may be at risk of skin cancer, as sun blocks require constant re-application, fade as they are exposed to sunlight, and often protect only against UVB rays, not the UVA rays blamed for some skin cancers and photo-aging of skin.
People with more melanin in their skin have darker skin that is naturally more resistant to sun damage because the melanin which is actually part of the epidermis acts as a wonderful natural sunscreen against all kinds of UV radiation. The compound being tested at the University of Kentucky actually stimulates skin to produce more of its own melanin.
The result is not only a biologically authentic, natural-looking tan, but also increased protection from the sun. Although all of the work thus far has been done in an animal model of "humanized skin", D'Orazio and his team showed that the skin of a pale individual can be made to mimic the sun-resistant skin of another with a naturally darker complexion. Effects are temporary and last only as long as the lotion is applied, so people could build up their melanin production in advance of prolonged sun exposure such as a trip to the beach. Researchers are touting this approach as a novel way to protect individuals from cancer-causing sun damage.
"What is exciting to us as scientists and physicians is the possibility of reducing skin cancer by making skin more impervious to UV damage. The cosmetic effect does have a lot of people excited and that's great too. If this keeps even one person from going to a tanning bed and increasing their risk for skin cancer, then it will serve its purpose," said D'Orazio.
Study suggests possible new target for treating and preventing Alzheimer's
02.12.2016 | Oregon Health & Science University
The first analysis of Ewing's sarcoma methyloma opens doors to new treatments
01.12.2016 | IDIBELL-Bellvitge Biomedical Research Institute
Have you ever wondered how you see the world? Vision is about photons of light, which are packets of energy, interacting with the atoms or molecules in what...
A multi-institutional research collaboration has created a novel approach for fabricating three-dimensional micro-optics through the shape-defined formation of porous silicon (PSi), with broad impacts in integrated optoelectronics, imaging, and photovoltaics.
Working with colleagues at Stanford and The Dow Chemical Company, researchers at the University of Illinois at Urbana-Champaign fabricated 3-D birefringent...
In experiments with magnetic atoms conducted at extremely low temperatures, scientists have demonstrated a unique phase of matter: The atoms form a new type of quantum liquid or quantum droplet state. These so called quantum droplets may preserve their form in absence of external confinement because of quantum effects. The joint team of experimental physicists from Innsbruck and theoretical physicists from Hannover report on their findings in the journal Physical Review X.
“Our Quantum droplets are in the gas phase but they still drop like a rock,” explains experimental physicist Francesca Ferlaino when talking about the...
The Max Planck Institute for Physics (MPP) is opening up a new research field. A workshop from November 21 - 22, 2016 will mark the start of activities for an innovative axion experiment. Axions are still only purely hypothetical particles. Their detection could solve two fundamental problems in particle physics: What dark matter consists of and why it has not yet been possible to directly observe a CP violation for the strong interaction.
The “MADMAX” project is the MPP’s commitment to axion research. Axions are so far only a theoretical prediction and are difficult to detect: on the one hand,...
Broadband rotational spectroscopy unravels structural reshaping of isolated molecules in the gas phase to accommodate water
In two recent publications in the Journal of Chemical Physics and in the Journal of Physical Chemistry Letters, researchers around Melanie Schnell from the Max...
16.11.2016 | Event News
01.11.2016 | Event News
14.10.2016 | Event News
05.12.2016 | Power and Electrical Engineering
05.12.2016 | Information Technology
05.12.2016 | Earth Sciences