An organic compound that creates a realistic beachy glow while inducing a natural sun block effect in your skin may be just around the corner, as scientists at the University of Kentucky are testing a treatment that enhances melanin production in animal models.
"We are in the process of evaluating forskolin, a derivative of the plant Pletranthus barbatus, for safety when applied to the skin. We know it stimulates melanin, but we need to know that it does so without adverse effect. So far, results are promising," said Dr. John D'Orazio of the UK Department of Pediatrics,the Markey Cancer Center and the Graduate Center for Toxicology.
Many people use sunless tanning products to achieve a tan look without risking the UV damage that causes skin cancer and wrinkles. However, sunless tanners currently on the market use a chemical that dyes skin a brown or orange shade. With no sun protection, skin remains vulnerable to burns and damage. Some people become frustrated with the tricky application of sunless tanners (as anyone who has ever left the house with orange knees and elbows can attest) and either give up entirely, or turn to the sun and tanning beds. Getting a tan either by sitting out in the sun or in a tanning bed currently comes with the bad side effects of ultraviolet radiation, namely sun spots, skin thickening and skin cancer. This new approach uses a lotion that fools the skin into thinking it has been out in the sun (causing natural tanning to happen) without the bad side effects of UV light.
Even those who do not desire a tanned look and use copious amounts of sun block may be at risk of skin cancer, as sun blocks require constant re-application, fade as they are exposed to sunlight, and often protect only against UVB rays, not the UVA rays blamed for some skin cancers and photo-aging of skin.
People with more melanin in their skin have darker skin that is naturally more resistant to sun damage because the melanin which is actually part of the epidermis acts as a wonderful natural sunscreen against all kinds of UV radiation. The compound being tested at the University of Kentucky actually stimulates skin to produce more of its own melanin.
The result is not only a biologically authentic, natural-looking tan, but also increased protection from the sun. Although all of the work thus far has been done in an animal model of "humanized skin", D'Orazio and his team showed that the skin of a pale individual can be made to mimic the sun-resistant skin of another with a naturally darker complexion. Effects are temporary and last only as long as the lotion is applied, so people could build up their melanin production in advance of prolonged sun exposure such as a trip to the beach. Researchers are touting this approach as a novel way to protect individuals from cancer-causing sun damage.
"What is exciting to us as scientists and physicians is the possibility of reducing skin cancer by making skin more impervious to UV damage. The cosmetic effect does have a lot of people excited and that's great too. If this keeps even one person from going to a tanning bed and increasing their risk for skin cancer, then it will serve its purpose," said D'Orazio.
Researchers identify new way to unmask melanoma cells to the immune system
17.01.2018 | Duke University Medical Center
Study advances gene therapy for glaucoma
17.01.2018 | University of Wisconsin-Madison
What enables electrons to be transferred swiftly, for example during photosynthesis? An interdisciplinary team of researchers has worked out the details of how...
For the first time, scientists have precisely measured the effective electrical charge of a single molecule in solution. This fundamental insight of an SNSF Professor could also pave the way for future medical diagnostics.
Electrical charge is one of the key properties that allows molecules to interact. Life itself depends on this phenomenon: many biological processes involve...
At the JEC World Composite Show in Paris in March 2018, the Fraunhofer Institute for Laser Technology ILT will be focusing on the latest trends and innovations in laser machining of composites. Among other things, researchers at the booth shared with the Aachen Center for Integrative Lightweight Production (AZL) will demonstrate how lasers can be used for joining, structuring, cutting and drilling composite materials.
No other industry has attracted as much public attention to composite materials as the automotive industry, which along with the aerospace industry is a driver...
Scientists at Tokyo Institute of Technology (Tokyo Tech) and Tohoku University have developed high-quality GFO epitaxial films and systematically investigated their ferroelectric and ferromagnetic properties. They also demonstrated the room-temperature magnetocapacitance effects of these GFO thin films.
Multiferroic materials show magnetically driven ferroelectricity. They are attracting increasing attention because of their fascinating properties such as...
The oceans are the largest global heat reservoir. As a result of man-made global warming, the temperature in the global climate system increases; around 90% of...
08.01.2018 | Event News
11.12.2017 | Event News
08.12.2017 | Event News
17.01.2018 | Ecology, The Environment and Conservation
17.01.2018 | Physics and Astronomy
17.01.2018 | Awards Funding