Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Pre-eclampsia kidney disease link

03.03.2006


Pre-eclampsia is a complication in pregnancy occurring in approximately eight percent of all pregnancies. It is characterised by elevated blood pressure and protein in the urine. It generally develops after 20 weeks of pregnancy.



Medical doctor and researcher Bjoern Egil Vikse from the Department of Medicine at University of Bergeb is the first author of an upcoming article in the March issue of the Journal of the American Society of Nephrology.

Vikse explains that there were two reasons for becoming involved in this work. The first was that a collegaue had previously found a strong correlation between pre-eclampsia and a later incidence of cardiovascular disease. The second is that UiB researchers have a unique research tool. They have access to two large databases: one is a birth registry; the other is a kidney biopsy registry. This enables them to use large, well-documented data pools in their work.


The Birth Registry provided Vikse with data from 1967 and the Kidney Biopsy Registry dates from 1988.

Unexpectedly strong correlation

Vikse and his colleagues first compared data from the two registries to see if there was a correlation between the children of mothers who had experienced pre-eclampsia and incidence of kidney disease in these children. They found no correlation.

They then compared the two databases for a possible correlation between the incidence of pre-eclampsia and later incidence of kidney disease in the mothers and found an unexpectedly strong result.

-We were amazed that the correlation was so strong," says Vikse. The data showed that pre-eclampsia alone was responsible for the mothers having a 3.3% increased risk of developing kidney disease later. If, in addition, the child had a low birth weight, the risk increased to a 4.8% increased risk with low birth-weight and a dramatic17% increased risk with very low birth-weight.

Another unexpected finding was that the increased risk was not associated with any particular kidney disease: all kidney diseases had a similar increased risk.

-You would expect the risk increase to be linked to a particular disease," explains Vikse. "It was most unusual to find that this was not the case."

Future directions

Vikse explains that the researchers will now try to characterise the correlation further as well as checking for correlations with other medical conditions such as kidney failure. Studies into the development of both pre-eclampsia and kidney disease are also needed to see if there are any similarities between the mechanisms by which both medical conditions develop.

According to Vikse, there are also more far-reaching consequences as well. This result suggests that information about having experienced a pregnancy with pre-eclampsia should be included in a woman’s medical history record. Such women need to be followed up for the rest of their lives because of their increased risk of cardiovascular and kidney disease.

Bjorn Egil Vikse | alfa
Further information:
http://www.uib.no/info/english/

More articles from Health and Medicine:

nachricht Nanoparticles as a Solution against Antibiotic Resistance?
15.12.2017 | Friedrich-Schiller-Universität Jena

nachricht Plasmonic biosensors enable development of new easy-to-use health tests
14.12.2017 | Aalto University

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: First-of-its-kind chemical oscillator offers new level of molecular control

DNA molecules that follow specific instructions could offer more precise molecular control of synthetic chemical systems, a discovery that opens the door for engineers to create molecular machines with new and complex behaviors.

Researchers have created chemical amplifiers and a chemical oscillator using a systematic method that has the potential to embed sophisticated circuit...

Im Focus: Long-lived storage of a photonic qubit for worldwide teleportation

MPQ scientists achieve long storage times for photonic quantum bits which break the lower bound for direct teleportation in a global quantum network.

Concerning the development of quantum memories for the realization of global quantum networks, scientists of the Quantum Dynamics Division led by Professor...

Im Focus: Electromagnetic water cloak eliminates drag and wake

Detailed calculations show water cloaks are feasible with today's technology

Researchers have developed a water cloaking concept based on electromagnetic forces that could eliminate an object's wake, greatly reducing its drag while...

Im Focus: Scientists channel graphene to understand filtration and ion transport into cells

Tiny pores at a cell's entryway act as miniature bouncers, letting in some electrically charged atoms--ions--but blocking others. Operating as exquisitely sensitive filters, these "ion channels" play a critical role in biological functions such as muscle contraction and the firing of brain cells.

To rapidly transport the right ions through the cell membrane, the tiny channels rely on a complex interplay between the ions and surrounding molecules,...

Im Focus: Towards data storage at the single molecule level

The miniaturization of the current technology of storage media is hindered by fundamental limits of quantum mechanics. A new approach consists in using so-called spin-crossover molecules as the smallest possible storage unit. Similar to normal hard drives, these special molecules can save information via their magnetic state. A research team from Kiel University has now managed to successfully place a new class of spin-crossover molecules onto a surface and to improve the molecule’s storage capacity. The storage density of conventional hard drives could therefore theoretically be increased by more than one hundred fold. The study has been published in the scientific journal Nano Letters.

Over the past few years, the building blocks of storage media have gotten ever smaller. But further miniaturization of the current technology is hindered by...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

See, understand and experience the work of the future

11.12.2017 | Event News

Innovative strategies to tackle parasitic worms

08.12.2017 | Event News

AKL’18: The opportunities and challenges of digitalization in the laser industry

07.12.2017 | Event News

 
Latest News

Engineers program tiny robots to move, think like insects

15.12.2017 | Power and Electrical Engineering

One in 5 materials chemistry papers may be wrong, study suggests

15.12.2017 | Materials Sciences

New antbird species discovered in Peru by LSU ornithologists

15.12.2017 | Life Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>