Melatonin in cancer
The role of melatonin for the treatment of cancer is looking compelling, according to a new study published in the Journal of Pineal Research. Researchers say that the results are so compelling that cancer funding agencies should be eager to support clinical trials to evaluate its therapeutic role in a variety of cancers.
Melatonin is a hormone naturally found in humans. Its association with cancer has been shown in many studies assessing links between shift work and cancer rates, and shown a consistent relationship. The association between melatonin levels and cancer progression has suggested to some that melatonin may be a modifier of cancer progression. In this latest study, researchers examined all clinical trials assessing the role of melatonin as a therapy for solid tumor cancers. They used a methodology called meta-analysis, a technique of analyzing multiple studies. The authors reviewed 10 randomized clinical trials that included a total of 643 cancer patients with a variety of different solid tumor cancers. The types of cancers involved included lung, brain, skin, renal and breast cancer. "In this analysis, the effects appeared to be consistent across studies" say the authors. The researchers examined the effect of large doses of melatonin (10-40mg/day) on survival rates at one year. Melatonin reduced the risk of death at one year by 34%. "Effects this large certainly warrant further clinical trials" say the authors. The study also showed that melatonin was predominantly safe and had a beneficial effect on sleep patterns of patients.
Edward Mills | EurekAlert!
Researchers identify new way to unmask melanoma cells to the immune system
17.01.2018 | Duke University Medical Center
Study advances gene therapy for glaucoma
17.01.2018 | University of Wisconsin-Madison
What enables electrons to be transferred swiftly, for example during photosynthesis? An interdisciplinary team of researchers has worked out the details of how...
For the first time, scientists have precisely measured the effective electrical charge of a single molecule in solution. This fundamental insight of an SNSF Professor could also pave the way for future medical diagnostics.
Electrical charge is one of the key properties that allows molecules to interact. Life itself depends on this phenomenon: many biological processes involve...
At the JEC World Composite Show in Paris in March 2018, the Fraunhofer Institute for Laser Technology ILT will be focusing on the latest trends and innovations in laser machining of composites. Among other things, researchers at the booth shared with the Aachen Center for Integrative Lightweight Production (AZL) will demonstrate how lasers can be used for joining, structuring, cutting and drilling composite materials.
No other industry has attracted as much public attention to composite materials as the automotive industry, which along with the aerospace industry is a driver...
Scientists at Tokyo Institute of Technology (Tokyo Tech) and Tohoku University have developed high-quality GFO epitaxial films and systematically investigated their ferroelectric and ferromagnetic properties. They also demonstrated the room-temperature magnetocapacitance effects of these GFO thin films.
Multiferroic materials show magnetically driven ferroelectricity. They are attracting increasing attention because of their fascinating properties such as...
The oceans are the largest global heat reservoir. As a result of man-made global warming, the temperature in the global climate system increases; around 90% of...
08.01.2018 | Event News
11.12.2017 | Event News
08.12.2017 | Event News
18.01.2018 | Life Sciences
18.01.2018 | Life Sciences
18.01.2018 | Earth Sciences