Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Statins protect from death from pneumonia

25.07.2005


Patients hospitalised because of pneumonia are at less risk of dying from the disease if they have been taking the widely used cholesterol-lowering drugs ’statins’ before hospital admission. These results, published today in the Open Access journal Respiratory Research, suggest another beneficial use of statins, which are prescribed to an increasing number of patients to prevent and treat high cholesterol, diabetes, heart disease and vascular disease.



Pneumonia is the seventh most common cause of death and the leading cause of death from infection in the USA, where it kills up to 40,000 people every year – those most at risk are very young children, elderly people and patients with underlying health problems such as AIDS or chronic obstructive pulmonary disease (CPOD). The disease is caused by viruses or bacteria, which are becoming resistant to the antibiotics used to treat bacterial pneumonia.

Eric Mortensen and colleagues, from the University of Texas Health Centre at San Antonio measured the risk of dying from pneumonia in patients admitted with pneumonia who were taking statins prior to their entry into hospital. They compared it with the risk of dying from the disease in pneumonia patients who were not taking statins. The authors used the Pneumonia Severity Index to rate the risk of dying within 30 days of admission to hospital in the two groups of patients. The results of their statistical analysis show that patients who were on a statin when they entered hospital were 2.8 times less likely to die than patients who were not on statins.


"Prior outpatient statin use was associated with decreased mortality in patients hospitalized with community-acquired pneumonia despite their use being associated with comorbid illnesses likely to contribute to increased mortality", write the authors.

More research is needed to explain the protective effect of statins on patients suffering from pneumonia. Statins act on the cholesterol-regulating enzyme HMG-CoA reductase, but they are also known to affect the immune system and this might explain their effect on pneumonia patients.

Juliette Savin | EurekAlert!
Further information:
http://www.biomedcentral.com

More articles from Health and Medicine:

nachricht Nanoparticles as a Solution against Antibiotic Resistance?
15.12.2017 | Friedrich-Schiller-Universität Jena

nachricht Plasmonic biosensors enable development of new easy-to-use health tests
14.12.2017 | Aalto University

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: First-of-its-kind chemical oscillator offers new level of molecular control

DNA molecules that follow specific instructions could offer more precise molecular control of synthetic chemical systems, a discovery that opens the door for engineers to create molecular machines with new and complex behaviors.

Researchers have created chemical amplifiers and a chemical oscillator using a systematic method that has the potential to embed sophisticated circuit...

Im Focus: Long-lived storage of a photonic qubit for worldwide teleportation

MPQ scientists achieve long storage times for photonic quantum bits which break the lower bound for direct teleportation in a global quantum network.

Concerning the development of quantum memories for the realization of global quantum networks, scientists of the Quantum Dynamics Division led by Professor...

Im Focus: Electromagnetic water cloak eliminates drag and wake

Detailed calculations show water cloaks are feasible with today's technology

Researchers have developed a water cloaking concept based on electromagnetic forces that could eliminate an object's wake, greatly reducing its drag while...

Im Focus: Scientists channel graphene to understand filtration and ion transport into cells

Tiny pores at a cell's entryway act as miniature bouncers, letting in some electrically charged atoms--ions--but blocking others. Operating as exquisitely sensitive filters, these "ion channels" play a critical role in biological functions such as muscle contraction and the firing of brain cells.

To rapidly transport the right ions through the cell membrane, the tiny channels rely on a complex interplay between the ions and surrounding molecules,...

Im Focus: Towards data storage at the single molecule level

The miniaturization of the current technology of storage media is hindered by fundamental limits of quantum mechanics. A new approach consists in using so-called spin-crossover molecules as the smallest possible storage unit. Similar to normal hard drives, these special molecules can save information via their magnetic state. A research team from Kiel University has now managed to successfully place a new class of spin-crossover molecules onto a surface and to improve the molecule’s storage capacity. The storage density of conventional hard drives could therefore theoretically be increased by more than one hundred fold. The study has been published in the scientific journal Nano Letters.

Over the past few years, the building blocks of storage media have gotten ever smaller. But further miniaturization of the current technology is hindered by...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

See, understand and experience the work of the future

11.12.2017 | Event News

Innovative strategies to tackle parasitic worms

08.12.2017 | Event News

AKL’18: The opportunities and challenges of digitalization in the laser industry

07.12.2017 | Event News

 
Latest News

Engineers program tiny robots to move, think like insects

15.12.2017 | Power and Electrical Engineering

One in 5 materials chemistry papers may be wrong, study suggests

15.12.2017 | Materials Sciences

New antbird species discovered in Peru by LSU ornithologists

15.12.2017 | Life Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>