Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Research urgently needed to treat blood clots in children

18.04.2005


Potentially deadly blood clots are being missed in children, and more research and awareness is needed in the medical community, according to a study done in part at the University of Alberta.



"We don’t think of blood clots occurring in children, but they do," said Dr. Patricia Massicotte, a professor of pediatrics at the University of Alberta, and one of the study’s authors.

A review of treatments for pulmonary thromboembolism (PTE) in children, conducted by the University of Alberta, the Edmonton Stollery Children’s Hospital and The Hospital for Sick Children in Toronto, revealed an acute need for more research into diagnosing the condition, whose symptoms can be misleading.


Review of data on 405 children who died in specialized pediatric hospitals in Canada between 1991-97 revealed that three per cent of the deaths were attributable to blood clots. "The condition does kill and it can also cause long-term cardiac problems or respiratory problems," Dr. Massicotte said.

The review results appear in the March, 2005 issue of Pediatric Radiology.

The condition, which exists in children ranging from premature infants to the late teens, is often not discovered until the autopsy stage. PTE most frequently exists in children who suffer from underlying conditions such as heart disease or cancer. Blood clots can be brought on by several risk factors and causes including burns, heart disease, dehydration, obesity, renal disease, shock and surgery.

One of the highest risk factors for blood clots in children is a central venous line, a large catheter inserted into the body to administer medication or nutrients. The line can damage vessel walls. But at the same time, the line is needed to help care for children suffering illness or trauma, and that makes recognizing the symptoms of PTE all the more vital, Dr. Massicotte said.

While the causes of blood clots in 30 to 40 per cent of adults have unknown origins, to their surprise, the researchers discovered in the review that only four per cent of the clots in children presented without any risk factors, Dr. Massicotte noted.

"The other 96 per cent had at least two or more known risk factors. The expert care centres (pediatric hospitals) know that children develop blood clots, but there are a lot of other health professionals who still don’t recognize the signs and symptoms."

Further research is needed, exploring such options as smaller catheters for pediatric patients, as well as clinical trials in using blood-thinners as preventive therapy. Currently, thinners are used only after a child develops clots.

Traditionally, researching more invasive treatment options for children has been regarded with reluctance, Dr. Massicotte said. "Because babies and children are so cute and innocent, we are reluctant to do studies, but we are not benefiting them at all by doing that."

Bev Betkowski | EurekAlert!
Further information:
http://www.ualberta.ca

More articles from Health and Medicine:

nachricht A promising target for kidney fibrosis
21.04.2017 | Brigham and Women's Hospital

nachricht Stem cell transplants: activating signal paths may protect from graft-versus-host disease
20.04.2017 | Technische Universität München

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Deep inside Galaxy M87

The nearby, giant radio galaxy M87 hosts a supermassive black hole (BH) and is well-known for its bright jet dominating the spectrum over ten orders of magnitude in frequency. Due to its proximity, jet prominence, and the large black hole mass, M87 is the best laboratory for investigating the formation, acceleration, and collimation of relativistic jets. A research team led by Silke Britzen from the Max Planck Institute for Radio Astronomy in Bonn, Germany, has found strong indication for turbulent processes connecting the accretion disk and the jet of that galaxy providing insights into the longstanding problem of the origin of astrophysical jets.

Supermassive black holes form some of the most enigmatic phenomena in astrophysics. Their enormous energy output is supposed to be generated by the...

Im Focus: A Quantum Low Pass for Photons

Physicists in Garching observe novel quantum effect that limits the number of emitted photons.

The probability to find a certain number of photons inside a laser pulse usually corresponds to a classical distribution of independent events, the so-called...

Im Focus: Microprocessors based on a layer of just three atoms

Microprocessors based on atomically thin materials hold the promise of the evolution of traditional processors as well as new applications in the field of flexible electronics. Now, a TU Wien research team led by Thomas Müller has made a breakthrough in this field as part of an ongoing research project.

Two-dimensional materials, or 2D materials for short, are extremely versatile, although – or often more precisely because – they are made up of just one or a...

Im Focus: Quantum-physical Model System

Computer-assisted methods aid Heidelberg physicists in reproducing experiment with ultracold atoms

Two researchers at Heidelberg University have developed a model system that enables a better understanding of the processes in a quantum-physical experiment...

Im Focus: Glacier bacteria’s contribution to carbon cycling

Glaciers might seem rather inhospitable environments. However, they are home to a diverse and vibrant microbial community. It’s becoming increasingly clear that they play a bigger role in the carbon cycle than previously thought.

A new study, now published in the journal Nature Geoscience, shows how microbial communities in melting glaciers contribute to the Earth’s carbon cycle, a...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Expert meeting “Health Business Connect” will connect international medical technology companies

20.04.2017 | Event News

Wenn der Computer das Gehirn austrickst

18.04.2017 | Event News

7th International Conference on Crystalline Silicon Photovoltaics in Freiburg on April 3-5, 2017

03.04.2017 | Event News

 
Latest News

New quantum liquid crystals may play role in future of computers

21.04.2017 | Physics and Astronomy

A promising target for kidney fibrosis

21.04.2017 | Health and Medicine

Light rays from a supernova bent by the curvature of space-time around a galaxy

21.04.2017 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>