Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Insight Into The Origins Of The Aids Epidemic May Offer New Treatment Approaches

11.01.2005


Medical Research Council (MRC) scientists have uncovered an important clue to understanding the origins of the AIDS epidemic. The work suggests that harnessing natural mechanisms of resistance to HIV infection might provide new methods for combating AIDS.



The research team at the MRC’s National Institute for Medical Research pinpointed crucial differences in a gene found in rhesus monkeys that can prevent HIV infection, and its human counterpart, that cannot.

The differences indicate that HIV infection would not have become established in the human population if the form of the gene present in certain monkeys had also been present in humans. More importantly, the studies reveal that only a single change to the human gene is needed to enable it to interfere with the replication process of the HIV virus and prevent infection.


Lead scientist, Dr Jonathan Stoye, said: “This discovery has significant implications for the development of effective gene therapy to combat AIDS. “In theory, it should be possible to take cells from an HIV-infected individual, make them resistant to HIV infection with the modified gene and reintroduce them into the patient. These cells could then block progression to AIDS.” “Alternatively we could seek for drugs that activate the human gene against HIV.”

The research findings are published in full in this week’s edition of Current Biology.

According to the latest UNAIDS figures, at the end of 2004, 39.4 million people worldwide – 37.2 million adults and 2.2 million children younger than 15 years – are living with HIV/AIDS.

HIV stands for ’human immunodeficiency virus’. HIV is a retrovirus that infects cells of the human immune system and destroys or impairs their function. Infection with this virus results in the progressive depletion of the immune system, leading to ’immune deficiency’, or AIDS. AIDS stands for ’acquired immunodeficiency syndrome’ and describes the collection of symptoms and infections associated with acquired deficiency of the immune system.

Press Office | alfa
Further information:
http://www.mrc.ac.uk

More articles from Health and Medicine:

nachricht Oxygen can wake up dormant bacteria for antibiotic attacks
08.12.2016 | Penn State

nachricht NTU scientists build new ultrasound device using 3-D printing technology
07.12.2016 | Nanyang Technological University

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Significantly more productivity in USP lasers

In recent years, lasers with ultrashort pulses (USP) down to the femtosecond range have become established on an industrial scale. They could advance some applications with the much-lauded “cold ablation” – if that meant they would then achieve more throughput. A new generation of process engineering that will address this issue in particular will be discussed at the “4th UKP Workshop – Ultrafast Laser Technology” in April 2017.

Even back in the 1990s, scientists were comparing materials processing with nanosecond, picosecond and femtosesecond pulses. The result was surprising:...

Im Focus: Shape matters when light meets atom

Mapping the interaction of a single atom with a single photon may inform design of quantum devices

Have you ever wondered how you see the world? Vision is about photons of light, which are packets of energy, interacting with the atoms or molecules in what...

Im Focus: Novel silicon etching technique crafts 3-D gradient refractive index micro-optics

A multi-institutional research collaboration has created a novel approach for fabricating three-dimensional micro-optics through the shape-defined formation of porous silicon (PSi), with broad impacts in integrated optoelectronics, imaging, and photovoltaics.

Working with colleagues at Stanford and The Dow Chemical Company, researchers at the University of Illinois at Urbana-Champaign fabricated 3-D birefringent...

Im Focus: Quantum Particles Form Droplets

In experiments with magnetic atoms conducted at extremely low temperatures, scientists have demonstrated a unique phase of matter: The atoms form a new type of quantum liquid or quantum droplet state. These so called quantum droplets may preserve their form in absence of external confinement because of quantum effects. The joint team of experimental physicists from Innsbruck and theoretical physicists from Hannover report on their findings in the journal Physical Review X.

“Our Quantum droplets are in the gas phase but they still drop like a rock,” explains experimental physicist Francesca Ferlaino when talking about the...

Im Focus: MADMAX: Max Planck Institute for Physics takes up axion research

The Max Planck Institute for Physics (MPP) is opening up a new research field. A workshop from November 21 - 22, 2016 will mark the start of activities for an innovative axion experiment. Axions are still only purely hypothetical particles. Their detection could solve two fundamental problems in particle physics: What dark matter consists of and why it has not yet been possible to directly observe a CP violation for the strong interaction.

The “MADMAX” project is the MPP’s commitment to axion research. Axions are so far only a theoretical prediction and are difficult to detect: on the one hand,...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

ICTM Conference 2017: Production technology for turbomachine manufacturing of the future

16.11.2016 | Event News

Innovation Day Laser Technology – Laser Additive Manufacturing

01.11.2016 | Event News

#IC2S2: When Social Science meets Computer Science - GESIS will host the IC2S2 conference 2017

14.10.2016 | Event News

 
Latest News

Closing the carbon loop

08.12.2016 | Life Sciences

Applicability of dynamic facilitation theory to binary hard disk systems

08.12.2016 | Physics and Astronomy

Scientists track chemical and structural evolution of catalytic nanoparticles in 3-D

08.12.2016 | Materials Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>