Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

False positive screening for cancer found to be frequent and costly

14.12.2004


Cancer screening tests can frequently produce false positive outcomes that may result not only in anxiety but also additional economic costs as well, according to research conducted by scientists at the Henry Ford Health System, Detroit, Mich., and published in the December issue of Cancer Epidemiology, Biomarkers & Prevention.



Among 1,087 individuals participating in a cancer screening trial who received a battery of tests for prostate, ovarian, colorectal and lung cancer, 43 percent had at least one false positive test result, according to Jennifer Elston Lafata, Ph.D., director of the Center for Health Services Research at the Henry Ford Health System and the lead author on the study.

"As new cancer screening tests are developed it is important to consider not only their potential clinical benefits, but also their potential for adverse effects," said Lafata, director of the Center for Health Services Research at the Henry Ford Health System. "One such adverse effect is the medical care costs associated with false positive cancer screening test results. Although such costs are often overlooked, we’ve shown they can be quite substantial."


Specifically, men who incurred a false positive result for either prostate, lung or colorectal cancer averaged $1,171 in additional medical care expenditures compared to men with all negative screens. More than half, 51 percent, of the men in the study had at least one false positive test. For women, 36 percent had false positive screening results. Women with a false positive screen for ovarian, colorectal or lung cancer experienced $1,024 more in follow-up medical care expenses compared to women with all negative results.

The study was funded by the National Cancer Institute and is part of a larger trial of the effectiveness of screening for prostate, lung, colorectal and ovarian cancers. "The results of this smaller study add to the growing body of evidence highlighting the importance of understanding not only the likely benefits of cancer screening, but also how the accuracy of screening tests impacts patients and medical care expenditures, and thus the overall cost-effectiveness of different screening alternatives," Lafata said.

"Although the clinical evidence for the use of these and many other new screening tests is still being developed, many such screening tests are already widely used in practice thereby resulting in what can be substantial additional medical care costs without known benefits."

Henry Ford Medical Group researchers who collaborated with Lafata in the study included Janine Simpkins, M.A., Lois Lamerato, Ph.D., Laila Poisson, M.S., George Divine, Ph.D., and Christine Cole Johnson, Ph.D.

Russell Vanderboom | EurekAlert!
Further information:
http://www.aacr.org

More articles from Health and Medicine:

nachricht Spanish scientists create a 3-D bioprinter to print human skin
24.01.2017 | Carlos III University of Madrid

nachricht Tracking movement of immune cells identifies key first steps in inflammatory arthritis
23.01.2017 | Massachusetts General Hospital

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Scientists spin artificial silk from whey protein

X-ray study throws light on key process for production

A Swedish-German team of researchers has cleared up a key process for the artificial production of silk. With the help of the intense X-rays from DESY's...

Im Focus: Quantum optical sensor for the first time tested in space – with a laser system from Berlin

For the first time ever, a cloud of ultra-cold atoms has been successfully created in space on board of a sounding rocket. The MAIUS mission demonstrates that quantum optical sensors can be operated even in harsh environments like space – a prerequi-site for finding answers to the most challenging questions of fundamental physics and an important innovation driver for everyday applications.

According to Albert Einstein's Equivalence Principle, all bodies are accelerated at the same rate by the Earth's gravity, regardless of their properties. This...

Im Focus: Traffic jam in empty space

New success for Konstanz physicists in studying the quantum vacuum

An important step towards a completely new experimental access to quantum physics has been made at University of Konstanz. The team of scientists headed by...

Im Focus: How gut bacteria can make us ill

HZI researchers decipher infection mechanisms of Yersinia and immune responses of the host

Yersiniae cause severe intestinal infections. Studies using Yersinia pseudotuberculosis as a model organism aim to elucidate the infection mechanisms of these...

Im Focus: Interfacial Superconductivity: Magnetic and superconducting order revealed simultaneously

Researchers from the University of Hamburg in Germany, in collaboration with colleagues from the University of Aarhus in Denmark, have synthesized a new superconducting material by growing a few layers of an antiferromagnetic transition-metal chalcogenide on a bismuth-based topological insulator, both being non-superconducting materials.

While superconductivity and magnetism are generally believed to be mutually exclusive, surprisingly, in this new material, superconducting correlations...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Sustainable Water use in Agriculture in Eastern Europe and Central Asia

19.01.2017 | Event News

12V, 48V, high-voltage – trends in E/E automotive architecture

10.01.2017 | Event News

2nd Conference on Non-Textual Information on 10 and 11 May 2017 in Hannover

09.01.2017 | Event News

 
Latest News

Breaking the optical bandwidth record of stable pulsed lasers

24.01.2017 | Physics and Astronomy

Choreographing the microRNA-target dance

24.01.2017 | Life Sciences

Spanish scientists create a 3-D bioprinter to print human skin

24.01.2017 | Health and Medicine

VideoLinks
B2B-VideoLinks
More VideoLinks >>>